vaccination tagged posts

A long-term analysis conducted by leading microbiologists at the Icahn School of Medicine at Mount Sinai reveals that antibody responses induced by COVID-19 vaccines are long-lasting. The study results, published online in the journal Immunity challenge the idea that mRNA-based vaccine immunity wanes quickly.

The emergence of SARS-CoV-2, the virus that causes COVID-19, in late 2019 sparked the global pandemic that is now in its fifth year. Vaccines that were developed at record speed have saved millions of lives. However, the emergence of SARS-CoV-2 variants and waning immunity have decreased the effectiveness of the vaccines against symptomatic disease. The common perception now is that mRNA-based vaccine-induced immunity wanes quickly.

However, this assumption is largely based...

Worldwide, more people die from tuberculosis (TB) than any other infectious disease, even though the vast majority were vaccinated. The vaccine just isn’t that reliable. But a new Nature study finds that simply changing the way the vaccine is administered could dramatically boost its protective power.

Researchers at the University of Pittsburgh School of Medicine and the National Institute of Allergy and Infectious Diseases (NIAID) discovered that intravenous TB vaccination is highly protecti...

S. J. Olshansky, L. Hayflick. The Role of the WI-38 Cell Strain in Saving Lives and Reducing Morbidity. AIMS Public Health, 2017; 4 (2): 127 DOI: 10.3934/publichealth.2017.2.127 Credit: National Cancer Institute

Nearly 200 million cases of polio, measles, mumps, rubella, varicella, adenovirus, rabies and hepatitis A – and ~450,000 deaths from these diseases – were prevented in the U.S. alone between 1963 and 2015 by vaccination. The study is published in AIMS Public Health. In 1963, vaccination against these infections became widespread, thanks to the development of a human cell strain that allowed vaccines to be produced safely. Globally, the vaccines developed from this strain and its derivatives prevented an ~4.5 billion cases of disease and saved more than 10 million lives.

Author S...

The vaccine targets tau proteins (pictured under the microscope) which form tangles in the brain, blocking supplies of vital nutrients to cells, which then die. This triggers the memory loss associated with the disease

In an unprecedented study, active vaccination in humans has resulted in a favorable immune response in 29 out of the 30 patients with only minor side effects. So far, many of the antibody drugs proposed to treat Alzheimer’s disease target only the amyloid plaques. Despite the latest clinical trial that is hailed as our best chance in the quest for treating AD, all later phase trials have failed with many causing severe side effects in the patients, such as abnormal accumulation of fluid and inflammation in the brain...