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Deciphering the Link between Skin Allergies and the Gut Microbiota

Fluorescence in-situ hybridization (FISH) is used to detect bacteria in the spleen of a normal mouse (left) and the spleen of a mouse with a MAVS deficiency (right). Spleen cells appear in blue; bacteria are stained red. Credit: Ana Hennino, David Bauché, Emilie Plantamura / CIRI

Fluorescence in-situ hybridization (FISH) is used to detect bacteria in the spleen of a normal mouse (left) and the spleen of a mouse with a MAVS deficiency (right). Spleen cells appear in blue; bacteria are stained red.
Credit: Ana Hennino, David Bauché, Emilie Plantamura / CIRI

Over the last few years, scientists have discovered connections between gut microbiota imbalances and various diseases. Now, in a study using mice, biologists from the CNRS, INSERM, and Claude Bernard Lyon 1 University – together with colleagues from the Institut Pasteur de Lille and the NIH (USA) – have revealed a surprising relationship between a viral detection system, the composition of the gut microbiota, and the development of skin allergies.

The number of microorganisms hosted in our digestive tracts is 10 ...

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