weight loss tagged posts

New battery-free, easily implantable weight-loss devices developed by engineers could offer a promising new weapon for battling the bulge. In laboratory testing, the devices helped rats shed almost 40% of their body weight. Results of the study were published today (Dec. 17, 2018) in the journal Nature Communications.

Measuring less than 1cm across, or about a third of the area of a U.S...

Boiled eggs Image: Pixabay

No extra risk for people with pre-diabetes or type 2 diabetes. University of Sydney researchers aim to help clear up conflicting dietary advice around egg consumption, as a new study finds eating up to 12 eggs per week for a year did not increase cardiovascular risk factors in people with pre-diabetes and type 2 diabetes.

Published in the American Journal of Clinical Nutrition, the research extends on a previous study that found similar results over a period of three months. Led by Dr Nick Fuller from the University’s Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders at the Charles Perkins Centre, the research was conducted with the University of Sydney’s Sydney Medical School and the Royal Prince Alfred Hospital.

In the initial trial, particip...

MC4R-dependent suppression of appetite by bone-derived lipocalin 2. Nature, 2017; DOI:

Scientists discover new mechanism that regulates food intake and blood sugar. Lipocalin 2 turns on neurons in the brain that have been previously linked to appetite suppression. The findings reveal a previously unknown mechanism for regulating the body’s energy balance and could lead to new targeted therapies for the treatment of obesity, type 2 diabetes, and other metabolic disorders.

“In recent years, studies at CUMC and elsewhere have shown that bone is an endocrine organ and produces hormones that affect brain development, glucose balance, kidney function, and male fertility,” says Stavroula Kousteni, PhD, associate professor of physiology and cellular biophysics (in medicine) at CUMC...

Highlights •PM20D1 is a secreted enzyme that regulates N-acyl amino acids in vivo •N-acyl amino acids are endogenous metabolites that uncouple mitochondria •Increased PM20D1 or N-acyl amino acid administration augments energy expenditure

Findings show potential for obesity treatment. Investigators have identified a natural molecular pathway that enables cells to burn off calories as heat rather than store them as fat. This raises the possibility of a new approach to treating and preventing obesity, diabetes, and other obesity-linked metabolic disorders including cancer.

Prof. Bruce Spiegelman, PhD discovered the mechanism in energy-burning brown and beige fat cells in mice...