West Nile virus tagged posts

How Antibodies access Neurons to Fight Infection

A cross-section of mouse dorsal root ganglia stained for memory CD4 T cells (green) and the vascular cell adhesion molecule, VCAM-1 (red) after six days of genital herpes challenge. Credit: Norifumi Iijima

A cross-section of mouse dorsal root ganglia stained for memory CD4 T cells (green) and the vascular cell adhesion molecule, VCAM-1 (red) after six days of genital herpes challenge. Credit: Norifumi Iijima

Yale scientists have solved a puzzle of the immune system – how antibodies enter the nervous system to control viral infections. Their finding may have implications for the prevention and treatment of a range of conditions, including herpes and Guillain-Barre syndrome, which has been linked to the Zika virus.

Many viruses, such as West Nile, Zika, HSV enter the nervous system, where they were thought to be beyond the reach of antibodies. Yale immunobiologists Dr...

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