white adipose tissue tagged posts

Scientists at the Terasaki Institute for Biomedical Innovation, in collaboration with the University of Maryland School of Pharmacy, have developed a new nanoparticle therapy that tackles obesity through two complementary mechanisms: converting energy-storing white fat into calorie-burning beige fat while simultaneously reducing obesity-related inflammation.

Their findings, published in the Journal of Controlled Release, are detailed in an article titled “Apigenin-loaded nanoparticles for obesity intervention through immunomodulation and adipocyte browning...

When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity. Now, UT Southwestern scientists have discovered a type of cell responsible, at least in mice, for triggering this inflammation in fat tissue. Their findings, published in Nature Metabolism, could eventually lead to new ways to treat obesity.

“The inflammation of fat cells in obese individuals is linked to many of the comorbidities we associate wit...