wound healing tagged posts

Efficient miR-92a downregulation in the skin upon treatment with caged antimiR-92a.

MicroRNAs are interesting target structures for new therapeutic agents. They can be blocked through synthetic antimiRs. However, to date it was not possible to use these only locally. Researchers at Goethe University Frankfurt have now successfully achieved this in the treatment of impaired wound healing with the help of light-inducible antimiRs.

MicroRNAs are small gene fragments which bond onto target structures in cells and in this way prevent certain proteins from forming. As they play a key role in the occurrence and manifestation of various diseases, researchers have developed what are known as antimiRs, which block microRNA function...

Credit: photo by Robin Hecker for The Ohio State University College of Medicine and The Ohio State University Center for Clinical and Translational Science Ohio State Researchers Create Bioelectric Bandage for Chronic Wounds (From left to right: Vish Subramaniam, PhD, Sashwati Roy, PhD and Shaurya Prakash, PhD)

Good news for the millions of people who suffer from skin wounds that won’t heal. A team of researchers at The Ohio State University has brought a potentially transformative solution to the problem by creating a portable adhesive patch that drives a continuous, small electrical current to stimulate healing and reduce the risk of infection...