Zebrafish tagged posts

Team Creates Synthetic Enzymes to Unravel Molecular Mysteries

Dr. P.C. Dave P. Dingal uses zebrafish to understand how developmental signaling is coordinated in animal embryos. Zebrafish are ideal models for observing signaling proteins because of their similarity with the human genome and their size.

A University of Texas at Dallas bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos.

The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed...

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Zebrafish teach Researchers more about Atrial Fibrillation

Stock photo of a zebrafish, which has not been part of the study. Photo: Colourbox
Stock photo of a zebrafish, which has not been part of the study. Photo: Colourbox

Researchers from the Faculty of Health and Medical Sciences have shown a possible link between a genetic variation and the widespread type of cardiac arrhythmia, atrial fibrillation.

The scientists conducted the study in zebrafish, which is a recognised scientific animal model within cardiac research.

Here, researchers from the University of Copenhagen in Denmark and the Max Planck Institute in Germany put special focus on the gene pitx2c. The result came as a surprise to them, says Assistant Professor Pia Lundegaard from the Department of Biomedical Sciences.

‘It seems that we may also have to think of atrial fibrillation as an atrial cardiomyopathy – that is, a challenged heart – rather than...

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