Highlights
•Mexican ZIKV strain infects primary human fetal brain-derived neural stem cells
•ZIKV inhibits neuronal differentiation in a cell-strain-dependent manner
•Majority of differentiated ZIKV-infected cells are glial cells
•ZIKV-mediated transcriptome alteration is cell-strain-dependent
A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered the mechanisms that the Zika virus uses to alter brain development. These findings are detailed in Stem Cell Reports. There are currently 70 countries and territories reporting active Zika transmission, according to the World Health Organization...
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