Sertraline. Credit: http://www.neurosoup.com/sertraline-zoloft/
The study – conducted in nonhuman primates with brain structures and functions similar to those of humans – found that the antidepressant sertraline, a SSRI, Zoloft, significantly increased the volume of one brain region in depressed subjects but decreased the volume of two brain areas in non-depressed subjects.
“These observations are important for human health because Zoloft is widely prescribed for a number of disorders other than depression,” said Carol A. Shively, Ph.D., professor of pathology-comparative medicine at Wake Forest Baptist.
METHOD: 41 middle-aged female monkeys were fed a diet formulated to replicate that consumed by many Americans for 18 months, during which time depressive behavior in the animals was recor...
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