Category Astronomy/Space

DIAPH3 silencing reduces the population of stable MT and alters MT topology. NB. Inhibition of MT stability arising from DIAPH3 downregulation enhances susceptibility to MT poisons, and that the DIAPH3 network potentially reports taxane sensitivity in human

The biomarker – diaphanous-related formin-3 or DIAPH3 – participates in a protein interaction that makes cells rigid. The study found that when this biomarker is lost or lowered, cells become “deformable,” squeezing through tissue spaces, causing disease growth or progression. This phenomenon is known as an amoeboid phenotype.

ie DIAPH3 interacted with microtubules (MT), and its loss altered several parameters of MT dynamics as well as decreased polarized force generation, contractility, and response to substrate stiffness...

“This mountain is among the tallest features we’ve seen on Ceres to date,” said Dawn science team member Paul Schenk, a geologist at the Lunar and Planetary Institute, Houston. “It’s unusual that it’s not associated with a crater. Why is it sitting in the middle of nowhere? We don’t know yet, but we may find out with closer observations.”

Also puzzling is the famous #Occator crater, home to Ceres’ brightest spots. A new animation simulates the experience of a close flyover of this area. The crater takes its name from the Roman agriculture deity of harrowing, a method of pulverizing and smoothing soil.

In examining the way Occator’s bright spots reflect light at different wavelengths, the Dawn science team has not found evidence that is consistent with ice...

Fermi-LAT sky map with the celestial neighborhood of the newly discovered pulsar PSR J1906+0722 featuring several other gamma-ray pulsars (not labeled). The color scale shows the gamma-ray intensity. The dashed square at the centre encloses the position of the pulsar and the part of the sky shown in more detail in the figure below. Credit: Knispel/AEI/NASA/DOE/Fermi LAT Collaboration Read more at: http://phys.org/news/2015-08-scientists-elusive-gamma-ray-pulsar.html#jCp

Gamma-ray pulsars are remnants of explosions that end the lives of massive stars. They are highly-magnetized and rapidly rotating compact neutron stars. Like a cosmic lighthouse they emit gamma-ray photons in a characteristic pattern that repeats with every rotation...

Astronomers have uncovered a unique process for how the universe’s largest elliptical galaxies continue making stars long after their peak years of star birth. Hubble Space Telescope’s exquisite high resolution and UVlight sensitivity allowed the astronomers to see brilliant knots of hot, blue stars forming along the jets of active black holes found in the centers of giant elliptical galaxies.

Combining Hubble data with observations from a suite of ground-based and space telescopes, 2 independent teams found that that the black hole, jets, and newborn stars are all parts of a self-regulating cycle. High-energy jets shooting from the black hole heat a halo of surrounding gas, controlling the rate at which the gas cools and falls into the galaxy.

“Think of the gas surrounding a galaxy ...