Category Biology/Biotechnology

Metformin, a widely prescribed, safe and inexpensive drug for type 2 diabetes, is a first-line treatment that lowers blood sugar and improves the body’s response to insulin. The drug appears to trick cells into sensing an energy shortage, similar to what happens during fasting or dieting. This activates a key cellular energy sensor called AMPK, which helps trigger cellular waste cleanup and supports cellular repair. Now, a recent review suggests metformin might also help counter some effects of aging.

The researchers compiled decades of global research, from cellular and molecular studies to animal and human studies, to provide a comprehensive, unified picture of how metformin might affect aging and longevity...

The neuroactive potential of bacteria living in the human gut is associated with levels of key chemicals in the brain, according to a new study published in Molecular Psychiatry. The research team from the University of Surrey and the University of Roehampton found that microbial pathways involved in producing and breaking down neuroactive compounds were associated with levels of GABA and glutamate in specific regions of the human brain.

GABA and glutamate are two of the brain’s most important chemical messengers. GABA predominantly dampens neural activity, while glutamate promotes excitation...

When the ESA Earth observation mission FLEX launches into space on September 15, 2026, as scheduled, it will carry high-precision optical components from Jena, Germany. Researchers at the Fraunhofer Institute for Applied Optics and Precision Engineering IOF have developed and manufactured a silicon-based doubleslit assembly as well as two high-precision mirrors for the spectrometer on board the satellite. The spectrometer is designed to detect the fluorescence of plants excited by sunlight from Earth’s orbit. The data is expected to provide new insights into the photosynthetic activity, health, and stress levels of vegetation.

The FLEX mission will address the question: How much...

The U.S. Food and Drug Administration (FDA) on Tuesday authorized the first wearable sensor that continuously tracks ketones—chemicals the body makes when it burns fat instead of sugar for fuel.

It is also the first device anywhere to monitor ketones and blood sugar at the same time, the FDA said.

When ketones climb too high, they can cause diabetic ketoacidosis, or DKA. The American Diabetes Association warns that DKA can worsen within hours and lead to coma or death if it goes untreated.

Hospital admissions for DKA have risen 55% over the past decade, according to Abbott, which makes the device.

Early symptoms are often mistaken for a stomach bug or another common infection, which delays care. Most people also do not keep a blood ketone meter at home.

“Knowing that ...