Category Biology/Biotechnology

Study identifies Cause of Disruption in Brain linked to Psychiatric Disorder including Schizophrenia

Dopamine-dependent long term depression of mediated transmission profoundly disrupts normal synaptic transmission between hippocampus and PFC. These results show how dopaminergic activation induces long-term hypofunction of NMDARs, which can contribute to disordered functional connectivity, a characteristic that is a hallmark of psychiatric disorders such as schizophrenia.

Dopamine-dependent long term depression of mediated transmission profoundly disrupts normal synaptic transmission between hippocampus and PFC. These results show how dopaminergic activation induces long-term hypofunction of NMDARs, which can contribute to disordered functional connectivity, a characteristic that is a hallmark of psychiatric disorders such as schizophrenia. Credit: https://neurowiki2012.wikispaces.com/file/view/Reward_circuit.jpg/315908202/Reward_circuit.jpg

New research reveals mechanisms that trigger disruption in the brain’s communication channels linked to symptoms in psychiatric disorders. This research could have important implications for treating symptoms of brain disorders.

Many of our everyday cognitive functions such as learning and memory rely on normal communic...

Read More

Bacteria’s Secret Weapon Against Pesticides, Antibiotics Revealed

A. This image shows methyl phosphate. B. Methyl phosphonate. Phosphonate compounds are characterized by a direct link between carbon (C) and phosphorus (P), marked with red. C. The molecular structure of the C-P lyase complex. Credit: Ditlev E. Brodersen, Aarhus University

A. This image shows methyl phosphate. B. Methyl phosphonate. Phosphonate compounds are characterized by a direct link between carbon (C) and phosphorus (P), marked with red. C. The molecular structure of the C-P lyase complex. Credit: Ditlev E. Brodersen, Aarhus University

Bacteria exhibit extreme adaptability, which makes them capable of surviving in the most inhospitable conditions. New research results produced by Danish and British researchers now reveal the molecular details behind one of the secret weapons used by bacteria in their battle to survive under very nutrient-poor and even toxic conditions.

All living things need phosphate to grow, which is why several hundred million tons of phosphate fertilisers are used every year in agriculture throughout the world...

Read More

Snake Scales Protect Steel against Friction

 

A snake generates friction at the points needed to move forwards only and prevents its scales from being worn off by too much friction. Researchers of KIT have found a way to transfer this feature to components of movable systems. In this way, durability of hip prostheses, computer hard disks or smartphones might be enhanced.

“Friction and wear are two of the biggest challenges in systems of several individual components,” Christian Greiner of the Institute for Applied Materials says. A solution is found in nature: Snakes, such as the ball python, or lizards, such as the sandfish skink, use friction to move forwards, but can reduce it to a minimum thanks to their scales...

Read More

Coffee Drinking Tied to Reduced Risk of Colon Cancer Recurrence, but Don’t Pour a Cup Just Yet

Colon cancer patients who were heavy coffee drinkers had a far lower risk of dying or having their cancer return than those who did not drink coffee, with significant benefits starting at two to three cups a day. Patients who drank four cups of caffeinated coffee or more a day had half the rate of recurrence or death than noncoffee drinkers.

But, the researchers caution, cancer patients should not start ordering extra tall coffees. The study, the first to report such findings, does not prove a cause-and-effect relationship between coffee drinking and a lower risk of colon cancer recurrence. As other experts note, there may be differences between heavy coffee drinkers and abstainers that the research was not able to account for.

In recent years, many studies have pointed to coffee’s health...

Read More