Category Biology/Biotechnology

Researchers report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

Experiments published August 24 in the open access journal PLOS Biology show that phytosterols supplements were able to act in place of the lost cholesterol and prevent sensory dysfunction in mice.

Sensory cells in the inner ear called outer hair cells (OHCs) amplify sounds by changing their length. As we age, these cells lose their ability to stretch in response to sound, preventing sound amplification and leading to age-related hearing loss...

Neuroscientists and psychologists have been trying for decades to better understand how humans make decisions, in the hope to devise more effective interventions to promote healthy and beneficial lifestyle choices. Two brain regions that have been linked to decision-making are the orbitofrontal cortex (OFC) and the anterior cingulate cortex (ACC).

Researchers at University of California, Berkeley (UC Berkeley), have been conducting extensive research focusing on these two areas of the brain and exploring their involvement in decision-making...

Our behavior is controlled through neural circuits in the brain. Molecular disturbances can lead to stereotypical behavior, as seen in neuropsychiatric disorders such as obsessive-compulsive and autism spectrum disorders.

A research team has now demonstrated that the absence of two proteins, Intersectin1 and Intersectin2, in mice leads to disrupted neural signaling and compulsive repetitive behavior, which is also observed in patients with Intersectin 1 mutations. This supports the idea that such defects can cause neuropsychiatric diseases. The study is published in Proceedings of the National Academy of Sciences.

Our brain is essentially our body’s computer...

An analysis of a clinical trial of more than 2,500 people with Type 2 diabetes and kidney disease found that high levels of four biomarkers are strongly predictive for the development of heart and kidney issues.

A simple blood test may predict the risk of progressive heart and kidney disease in people with Type 2 diabetes and kidney disease, according to new research published today in the American Heart Association’s flagship journal Circulation.

“High levels of certain biomarkers are indicators of heart and kidney complications and may help predict future risk of disease progression,” said lead author James Januzzi, M.D...