Category Biology/Biotechnology

A stress-related chemical could initiate symptoms of depression

A stress-related chemical could initiate symptoms of depression
Excitatory neurotransmitter-Glu induces active FA generation in the mitochondria. Credit: Molecular Psychiatry (2025). DOI: 10.1038/s41380-025-03405-2

Depression, one of the most prevalent mental health disorders worldwide, is characterized by persistent feelings of sadness, impaired daily functioning and a loss of interest in daily activities, often along with altered sleeping and eating patterns. Past research findings suggest that stress can play a key role in the emergence of depressive symptoms, yet the biological processes via which it might increase the risk of depression remain poorly understood.

Researchers at Wenzhou Medical University, Capital Medical University and other institutes in China recently carried out a study investigating the biological processes that could ...

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Diabetes drugs may be changing cancer in surprising ways

Diabetes Drugs May Be Changing Cancer
Diabetes drugs taken every day by millions may secretly be shaping cancer risk in ways scientists are only beginning to understand. Credit: Shutterstock

Common diabetes drugs may do more than regulate blood sugar—they could also influence how cancers grow, spread, or slow down. Researchers are now unraveling how these medications affect immune function, inflammation, and tumor biology, with intriguing but still uncertain implications.

Researchers are taking a closer look at how medications used to treat diabetes may also influence cancer. While diabetes itself has long been associated with higher cancer risk, scientists are now investigating whether diabetes drugs play a direct role beyond controlling blood sugar levels and body weight...

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Short, intensive workouts can help fight bowel cancer

exercise
Credit: Pixabay/CC0 Public Domain

As many of us embark on an exercise or gym routine for the new year, research reveals that just 10 minutes of intense exercise could help fight cancer.

Short bursts of energetic activity can trigger rapid molecular changes in the bloodstream, shutting down bowel cancer growth and speeding up DNA damage repair, a new study has shown.

Researchers at Newcastle University have found that exercise increases the concentration of several small molecules in the blood—many linked to reducing inflammation, improving blood vessel function, and metabolism.

When these exercise-induced molecules were applied to bowel cancer cells in the lab, the activity of more than 1,300 genes was altered, including those involved in DNA repair, energy production, and c...

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First breathing ‘lung-on-chip’ developed using genetically identical cells

lung
Credit: Pixabay/CC0 Public Domain

Researchers at the Francis Crick Institute and AlveoliX have developed the first human lung-on-chip model using stem cells taken from only one person. These chips simulate breathing motions and lung disease in an individual, holding promise for testing treatments for infections like tuberculosis (TB) and delivering personalized medicine.

The research is published in the journal Science Advances.

Air sacs in the lungs called alveoli are the essential site of gas exchange and also an important barrier against inhaled viruses and bacteria that cause respiratory diseases like flu or TB.

Researchers have been working to recreate the battle between human cells and bacteria in the lab by building a lung-on-a-chip: small units of human lung on a plast...

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