Category Biology/Biotechnology

When it comes to chronic infections and cancer, a particular type of immune cell plays a central role in our defenses. Researchers at the University of Basel have uncovered the key to the tenacity of these immune cells in coping with the marathon that is fighting a chronic infection. Their results lay the foundations for more effective therapies and vaccination strategies.

Infected and abnormal cells have to go...

Obese fruit flies are the experimental subjects in a Nature Communications study of the causes of muscle function decline due to obesity. In humans, skeletal muscle plays a crucial role in metabolism, and muscle dysfunction due to human obesity can lead to insulin resistance and reduced energy levels.

Interestingly, studies in various animal models have shown that time-restricted feeding — a natural non-pharmaceutical intervention — protects against obesity, aging and circadian disruption in peripheral tissues such as skeletal muscle. However, the mechanisms underlying those benefits were not known.

In fruit flies — scientifically known as Drosophila melanogaster — obese Drosophila that are subje...

For almost 140 years, the origin and behaviour of an enigmatic cell type inside lymph nodes, called a tingible body macrophage, has remained a mystery. Now, for the first time, scientists at the Garvan Institute of Medical Research have tracked the cell’s lifecycle and function, with implications for our understanding of autoimmune disorders.

Autoimmune disease, which occurs when the immune system attacks the body, affects 5% of Australians and has a high chronic health burden worldwide, yet its causes are poorly understood.

“In living organisms, death happens all the time — and if you don’t clean up, the contents of the dead cells can trigger autoimmune diseases,” says...

Scientists have used seaweed to develop biodegradable health sensors, which could be applied like a second skin. Scientists at the University of Sussex have successfully trialed new biodegradable health sensors that could change the way we experience personal healthcare and fitness monitoring technology.

The team at Sussex have developed the new health sensors — such as those worn by runners or patients to monitor heart rate and temperature — using natural elements like rock salt, water and seaweed, combined with graphene. Because they are solely made with ingredients found in nature, the sensors are fully biodegradable, making them more environmentally friendly than commonly used rubber and plastic-based alternatives...