Category Biology/Biotechnology

Xenon gas inhalation reduced neurodegeneration and boosted protection in preclinical models of Alzheimer’s disease. Most treatments being pursued today to protect against Alzheimer’s disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and Washington University School of Medicine in St. Louis points to a novel — and noble — approach: using Xenon gas...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

The study, published in Nature Immunology, may lead to therapies that target the earliest stages of cancer. The findings bolster the idea that the inflammasome has a dual role: It promotes inflammation associated with poor outcomes in late cancer stages, but early on, it can help prevent cells from becoming cancerous in the first place.

“What was striking was that the in...

Our body isn’t just human—it’s home to trillions of microorganisms found in or on us. In fact, there are more microbes in our gut than there are stars in the Milky Way. These microbes are essential for human health, but scientists are still figuring out exactly what they do and how they help.

In a new study, published in Nature Microbiology, my colleagues and I explored how certain gut bacteria—a group known as Enterobacteriaceae—can protect us from harmful ones. These bacteria include species such as Escherichia coli (E coli). This is normally harmless in small amounts but can cause infections and other health problems if it grows too much.

We found that our gut environment—shaped by things like diet—plays a big role in keeping potentially harmful bacteria in check.

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University’s Ithaca campus.

The research is published in the journal Nature.

The human body has co-evolved with the beneficial microbes that live in the gut (termed the microbiota), resulting in mutually favorable relationships that aid in the d...