Category Biology/Biotechnology

New Immune Target to Treat Cardiovascular Disease discovered

supar cells blood vessels plaque
Justine Ross, Michigan Medicine

The protein, suPAR, has been found to cause atherosclerosis and kidney disease. Investigators say it’s the first immune target to treat cardiovascular disease, which affects over 1 billion people worldwide. Researchers believe treatment could be developed within five years.

For the longest time, clinicians have treated cardiovascular disease by focusing on diabetes and blood pressure control, reducing cholesterol using medications like aspirin and statins.

Despite these measures, heart disease remains the number one cause of death in the United States, with many patients having heart attacks even after their risk factors are controlled, says Salim Hayek, M.D...

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Blood-based Metabolic Signature Outperforms Standard Method for Predicting Diet, Disease Risk

Food blood vial collage
Getty Images

The study found that machine learning techniques improved diet prediction by 10-20%. When it comes to studying food and diet, it’s difficult to know what people are eating — let alone their risk of disease caused by what they eat.

Doctors and researchers usually ask people to fill out a long-from food frequency questionnaire that estimates caloric intake, food groups and nutrients. That relies on a person’s memory and may not provide the most accurate picture.

However, a research team led by a Michigan Medicine cardiologist have found a method using molecular profiling and machine learning to develop blood-based dietary signatures that more accurately predict both diet and the risk of cardiovascular disease and type 2 diabetes...

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Producing ‘Green’ Energy – literally – from Living Plant ‘Bio-Solar Cells’

Leaves of a succulent plant. Two pieces of metal marked “anode” and “cathode” are inserted into one leaf and connected to electrical wires.
The ice plant succulent shown here can become a living solar cell and power a circuit using photosynthesis.
Credit: Adapted from ACS Applied Materials & Interfaces, 2022, DOI: 10.1021/acsami.2c15123

Though plants can serve as a source of food, oxygen and décor, they’re not often considered to be a good source of electricity. But by collecting electrons naturally transported within plant cells, scientists can generate electricity as part of a “green,” biological solar cell. Now, researchers reporting in ACS Applied Materials & Interfaces have, for the first time, used a succulent plant to create a living “bio-solar cell” that runs on photosynthesis.

In all living cells, from bacteria and fungi to plants and animals, electrons are shuttled around as part of natural, biochemical proces...

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A Mediterranean Diet not only Boosts Health, but also Improves Fertility

pregnancy_ Med diet shutterstock_2167477639_web.jpg

With an emphasis on fruits, vegetables and legumes, the Mediterranean diet has long been applauded for its multiple health benefits. Now, new research shows that it may also help overcome infertility, making it a non-intrusive and affordable strategy for couples trying to conceive.

Conducted by Monash University, the University of the Sunshine Coast, and the University of South Australia, the review found that the Mediterranean diet can improve fertility, assisted reproductive technology (ART) success, and sperm quality in men.

Specifically, researchers identified that anti-inflammatory properties of a Mediterranean diet can improve couples’ chances of conception.

Infertility is a global health concern affecting 48 million couples and 186 million individuals worldwide.

Uni...

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