Category Biology/Biotechnology

Scientists discover Anti-Inflammatory molecules that Decline in the Aging Brain

The brain is comprised of lipids or fats, but the role of these molecules in health and disease remains unknown. The newly identified class of lipids, called SGDGs, decrease with aging, which suggests they may play a role in brain aging.
Credit: Salk Institute

The molecules, called SGDGs, may lead to new ways to treat age-related neurological diseases. Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolism changes, and many others. Now, a team of Salk Institute and UC San Diego scientists reveal another factor implicated in the aging process — a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects.

The research, published in Nature Chemical Biology on...

Read More

Largest Potentially Hazardous Asteroid detected in Eight Years

Artist’s impression of an asteroid that orbits closer to the Sun than Earth’s orbit

Twilight observations with the US Department of Energy-fabricated Dark Energy Camera at Cerro Tololo Inter-American Observatory in Chile, a Program of NSF’s NOIRLab, have enabled astronomers to spot three near-Earth asteroids (NEA) hiding in the glare of the Sun. These NEAs are part of an elusive population that lurks inside the orbits of Earth and Venus. One of the asteroids is the largest object that is potentially hazardous to Earth to be discovered in the last eight years.

An international team using the Dark Energy Camera (DECam) mounted on the Víctor M...

Read More

A Key Regulator of Cell Growth Deciphered

The SEA complex is composed of a cage-like core (SEACAT, blue) that regulates the activity of the wings (SEACIT, white and bright). © Ciencia Graficada

The mTOR protein plays a central role in cell growth, proliferation and survival. Its activity varies according to the availability of nutrients and some growth factors, including hormones. This protein is implicated in several diseases, including cancer, where its activity frequently increases...

Read More

Fighting Tumours with Magnetic Bacteria

Illustration of a blood vessel as well as the blood cells and the magnetic bacteria
Magnetic bacteria (grey) can squeeze through narrow intercellular spaces to cross the blood vessel wall and infiltrate tumours. (Visualisations: Yimo Yan / ETH Zurich)

Researchers at ETH Zurich are planning to use magnetic bacteria to fight cancerous tumours. They have now found a way for these microorganisms to effectively cross blood vessel walls and subsequently colonise a tumour.

Scientists around the world are researching how anti-cancer drugs can most efficiently reach the tumours they target. One possibility is to use modified bacteria as “ferries” to carry the drugs through the bloodstream to the tumours. Researchers at ETH Zurich have now succeeded in controlling certain bacteria so that they can effectively cross the blood vessel wall and infiltrate tumour tissue.

L...

Read More