Category Biology/Biotechnology

How a Cell’s Mitochondria make their Own Protein Factories

mitoribosomes
A subunit of a yeast mitoribosome (pink) compared to that of a human mitoribosome (purple). Although different, the two developing subunits have an assembly factor (green) in common. Credit: Sebastian Klinge

The findings shed a rare light on mitoribosomes, the unique ribosomes found within the cell’s mitochondria. Ribosomes, the tiny protein-producing factories within cells, are ubiquitous and look largely identical across the tree of life. Those that keep bacteria chugging along are, structurally, not much different from the ribosomes churning out proteins in our own human cells.

But even two organisms with similar ribosomes may display significant structural differences in the RNA and protein components of their mitoribosomes...

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Study identifies Potential Link between Oral Bacteria and Brain Abscesses

Bacteria known to cause oral infections may also be a contributory factor in patients developing potentially life-threatening abscesses on the brain, new research has shown. The study, published in the Journal of Dentistry, investigated brain abscesses and their association with bacteria that occur in the oral cavity. While this type of abscess is relatively uncommon, it can result in significant mortality and morbidity.

Researchers examined the records of 87 patients admitted to hospital with brain abscesses, and used microbiological data obtained from abscess sampling and peripheral cultures.

This allowed them to investigate the presence of oral bacteria in patients’ brain abscesses where a cause of the abscess had either been found, as was the case in just 35 patients, or not...

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Harvesting Light to Grow Food and Clean Energy Together

solar filters emit a red light over tomato plants in an outdoor research field at UC Davis
Solar filters emit a red light over tomato plants growing in a research field at UC Davis in 2022. The work further tests the findings of a UC Davis study showing plants in agrivoltaic systems respond best to the red spectrum of light while blue light is better used for energy production. (Andre Daccache/UC Davis)

Different light spectra serve different needs for agrivoltaics. People are increasingly trying to grow both food and clean energy on the same land to help meet the challenges of climate change, drought and a growing global population that just topped 8 billion. This effort includes agrivoltaics, in which crops are grown under the shade of solar panels, ideally with less water.

Now scientists from the University of California, Davis, are investigating how to better harvest ...

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Immunotherapy Eliminates Disease-causing Cells in Mice with MS-like Disease

Successful cancer treatment approach extended to autoimmune disease. Researchers have shown that the cancer therapy known as CAR-T can be applied to multiple sclerosis (MS), an autoimmune disease of the nervous system. The findings extend the powerful tool of immunotherapy to autoimmune diseases, a class of diseases that are often debilitating and difficult to treat.

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

Now, studying mice with an autoimmune disease similar to multiple sclerosis (MS), researchers at Washington University School of Medicine in St...

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