Category Biology/Biotechnology

A compound that both inhibits the MRSA superbug and renders it more vulnerable to antibiotics has been discovered by scientists at the University of Bath in the UK led by Dr Maisem Laabei and Dr Ian Blagbrough.

The novel compound – a polyamine – seems to destroy Staphylococcus aureus, the bacterium that causes (among other things) deadly Methicillin-resistant Staphylococcus aureus (MRSA) infections, by disrupting the pathogen’s cell membrane.

The compound was tested in-vitro against 10 different antibiotic-resistant strains of S. aureus, including some that are known to be resistant to vancomycin – the final drug of choice given to patients fighting an MRSA infection...

Amid much speculation and research about how our genetics affect the way we age, a University of California, Berkeley, study now shows that individual differences in our DNA matter less as we get older and become prone to diseases of aging, such as diabetes and cancer.

In a study of the relative effects of genetics, aging and the environment on how some 20,000 human genes are expressed, the researchers found that aging and environment are far more important than genetic variation in af...

Researchers from Johns Hopkins Medicine have discovered that the organization of different types of immune cells within pancreatic tumors is associated with how well patients with pancreatic cancer respond to treatment and how long they survive. The new findings, published Sept. 16 in Cancer Research, could eventually lead to new ways of treating pancreatic cancer, which has the highest mortality rate of all major cancers.

“Mapping the location of certain immune cells associated with a tumor could be a new biomarker to predict patient survival,” says Aleksander Popel, Ph.D...

For the very first time, a study led by Julian Chen and his group in Arizona State University’s School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution, has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

The central dogma of molecular biology specifies the order in which genetic information is transferred from DNA to make proteins. Messenger RNA molecules carry the genetic information from the DNA in the nucleus of the cell to the cytoplasm where the proteins are made. Messenger RNA acts as the messenger to build proteins.

“Actually, there are many RNAs (ribonucleic acids) that are not used to make proteins,”...