Category Biology/Biotechnology

A multi-institution study led by Rohan Dharmakumar, PhD, of Indiana University School of Medicine, has identified that iron drives the formation of fatty tissue in the heart and leads to chronic heart failure in about fifty percent of heart attack survivors. The discovery, recently published in Nature Communications, paves the way for treatments that have the potential to prevent heart failure in nearly half a million people a year in the United States, and many millions more worldwide.

“For the first time, we have identified a root cause of chronic heart failure following a heart attack,” Dharmakumar said.

Dharmakumar is executive director of IU’s Krannert Cardiovascular Researc...

The molecules, called SGDGs, may lead to new ways to treat age-related neurological diseases. Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolism changes, and many others. Now, a team of Salk Institute and UC San Diego scientists reveal another factor implicated in the aging process — a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects.

The research, published in Nature Chemical Biology on...

Twilight observations with the US Department of Energy-fabricated Dark Energy Camera at Cerro Tololo Inter-American Observatory in Chile, a Program of NSF’s NOIRLab, have enabled astronomers to spot three near-Earth asteroids (NEA) hiding in the glare of the Sun. These NEAs are part of an elusive population that lurks inside the orbits of Earth and Venus. One of the asteroids is the largest object that is potentially hazardous to Earth to be discovered in the last eight years.

An international team using the Dark Energy Camera (DECam) mounted on the Víctor M...

The mTOR protein plays a central role in cell growth, proliferation and survival. Its activity varies according to the availability of nutrients and some growth factors, including hormones. This protein is implicated in several diseases, including cancer, where its activity frequently increases...