Category Biology/Biotechnology

Hormone discovery could Predict Long Term Health of Men

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Researchers have discovered the vital role of a hormone, that develops in men during puberty, in providing an early prediction of whether they could develop certain diseases in later life.

Scientists from the University of Nottingham have discovered that the novel insulin-like peptide hormone, called INSL3, is consistent over long periods of time and is an important early biomarker for prediction of age-linked disease. Their latest findings have been published today in Frontiers in Endocrinology.

INSL3 is made by the same cells in the testes that make testosterone, but unlike testosterone which fluctuates throughout a man’s life, INSL3 remains consistent, with the level at puberty remaining largely the same throughout a man’s life, decreasing only slightly into old age...

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Researchers develop a Material that Mimics how the Brain Stores Information

First artificial synapse that reproduces learning during sleep. Universitat Autònoma de Barcelona researchers have developed a magnetic material capable of imitating the way the brain stores information. The material makes it possible to emulate the synapses of neurons and mimic, for the first time, the learning that occurs during deep sleep.

Neuromorphic computing is a new computing paradigm in which the behavior of the brain is emulated by mimicking the main synaptic functions of neurons. Among these functions is neuronal plasticity: the ability to store information or forget it depending on the duration and repetition of the electrical impulses that stimulate neurons, a plasticity that would be linked to learning and memory.

Among the materials that mimic neuron synapses, me...

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Study shows that Adaptive Immune Responses can cause Cellular Loss in the Aging-Related Brain

Study shows that adaptive immune responses can cause cellular loss in the aging brain
The cell type composition of scRNA-seq was analyzed and oligodendrocytes were separated into four different sub-clusters. Two previously unknown oligodendrocyte clusters appeared in aged mice, which were enriched in the white matter. One was associated with injury responses. Because this cluster was highly enriched in the aged white matter, it was named aging-related oligodendrocytes (Fig. 1b-c, e). Also a smaller interferon-responsive oligodendrocyte subpopulation (IRO) was characterized by the expression of genes commonly associated with an interferon response. Credit: Kaya et al.

Past neuroscience studies have consistently demonstrated that the aging of the mammalian nervous system is liked with a decline in the volume and functioning of white matter, nerve fibers found in deep brai...

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Brain Changes in Autism are far more sweeping than previously known, study finds

This shows a brain
The new study finds brain-wide changes in virtually all of the 11 cortical regions analyzed, regardless of whether they are higher critical association regions – those involved in functions such as reasoning, language, social cognition and mental flexibility – or primary sensory regions. Image is in the public domain

Brain changes in autism are comprehensive throughout the cerebral cortex rather than just particular areas thought to affect social behavior and language, according to a new UCLA-led study that significantly refines scientists’ understanding of how autism spectrum disorder (ASD) progresses at the molecular level.

The study, published today in Nature, represents a comprehensive effort to characterize ASD at the molecular level...

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