Category Biology/Biotechnology

Gut Microbe could hold Key to Help People Benefit from Healthy Foods

A gut microbe could hold a key to help people benefit from healthy foods
Graphical abstract. Credit: Cell (2024). DOI: 10.1016/j.cell.2024.06.018

In an analysis of more than 50,000 individuals from around the world, carriers of gut Blastocystis, a single-celled organism that has been labeled either a parasite or harmless organism but is commonly found in the digestive system, was linked to indicators of good cardiovascular health and decreased body fat.

The research is published in Cell by an international team led by investigators at Massachusetts General Hospital (MGH).

“Blastocystis’ effects on health and disease are controversial and likely context-dependent, but our research suggests that it may play a beneficial role in how diet impacts human health and disease,” said co-lead author Long H...

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Scientists discover New T cells and Genes related to Immune Disorders

A newly developed method called ReapTEC allowed the discovery of thousands of active bidirectional enhancers. Further analysis of GWAS data revealed that various immune-mediated diseases, like multiple sclerosis and rheumatoid arthritis, are related to genetic variations within these enhancers.

Researchers led by Yasuhiro Murakawa at the RIKEN Center for Integrative Medical Sciences (IMS) and Kyoto University in Japan and IFOM ETS in Italy have discovered several rare types of helper T cells that are associated with immune disorders such as multiple sclerosis, rheumatoid arthritis, and even asthma...

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Ointment containing DNA Molecules can Combat Allergic Contact Dermatitis

Ointment containing DNA molecules can combat allergic contact dermatitis
Fluorescence microscopic imaging of the skin treated with the aptamer cream: – The aptamers (here marked in pink) were applied to the top layer of the skin in the form of an ointment and also penetrate into the deeper dermal layers (nucleus: blue; antigen-presenting cells: green). Credit: Marlene Gottschalk

Researchers at the University of Bonn have isolated a DNA molecule that is suitable for combating allergic contact dermatitis in mice. The aptamer binds to certain immune system messenger substances, rendering them ineffective. This even works if the active ingredient is applied to the skin in the form of an ointment.

The working groups involved hope that aptamer creams such as this could also be suitable for treating other skin conditions...

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A New Brain-Inspired Artificial Dendritic Neural Circuit

Researchers at Tsinghua University recently introduced a new neuromorphic computational architecture designed to replicate the organization of synapses (i.e., connections between neurons) and the tree-like structure of dendrites (i.e., projections extending from the body of neurons).Read More