Category Biology/Biotechnology

A new study by investigators from Mass General Brigham has used next-generation imaging technology to discover that when the brain is falling asleep, it shows a coordinated shift in activity.

The researchers found that during NREM (non-rapid eye movement) sleep, parts of the brain that handle movement and sensory input stay active and keep using energy, while areas involved in thinking, memory and daydreaming quiet down and use less energy. Their results are published in Nature Communications.

“This research helps explain how the brain stays responsive to the outside world even as awareness fades during sleep,” said corresponding author Jingyuan Chen, Ph.D., an assistant investigator at the Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital.

Interval running condenses the powerful effects of regular running into shorter, high-intensity bursts. Research shows it can improve cardiovascular health, regulate blood sugar, and reduce body fat more effectively than longer steady runs. Just a few short sprints per session can deliver major fitness gains.

Running offers a wide range of advantages for both body and mind. It can protect against disease, improve mood, and even slow down the body’s natural aging process.

Yet about 31% of adults still don’t get enough physical activity, including running. The most common reason people give is simple — they don’t have enough time.

That’s where interval running comes in. It promises nearly all the same benefits of regular running, but in a fraction of the time.

What Is Interv...

Adults with gum disease may be more likely to have signs of damage to the brain’s white matter, called white matter hyperintensities, than people without gum disease, according to a study published in Neurology Open Access.

White matter refers to nerve fibers that help different parts of the brain communicate. Damage to this tissue can affect memory, thinking, balance and coordination and has been linked to higher stroke risk.

White matter hyperintensities are bright spots that appear on brain scans that are thought to reflect damaged white matter tissue. While the study found an association, it does not prove that gum disease causes white matter damage.

“This study shows a link between gum disease and white matter hyperintensities, suggesting...

For 25 years, scientists have studied “SuperAgers”—people aged 80 and above whose memory rivals those decades younger. Research reveals that their brains either resist Alzheimer’s-related plaques and tangles or remain resilient despite having them.

These individuals maintain a youthful brain structure, with a thicker cortex and unique neurons linked to memory and social skills. Insights from their biology and behavior could inspire new strategies to protect cognitive health into late life.

For the past 25 years, researchers at Northwestern Medicine have been examining people aged 80 and older, known as “SuperAgers,” to uncover why...