Category Biology/Biotechnology

One way cancer specialists detect the disease is by examining cells and bodily fluids under a microscope, a time-consuming and labor-intensive process called cytology. It involves visually inspecting tens of thousands to one million cells per slide for subtle 3D morphological changes that might signal the onset of cancer. But AI offers an approach that is potentially faster and more accurate.

In a new study published in the journal Nature, researchers demonstrate an AI-powered 3D scanning system that can automatically sort through samples and identify abnormal cells with performance approaching that of human experts.

Building digital models
The team developed a system called Whole-Slide Edge Tomo...

People have long given up on the search for the Fountain of Youth, a mythical spring that could reverse aging. But for some scientists, the hunt has not ended—it’s just moved to a different place. These modern-day Ponce de Leóns are investigating whether gut microbes hold the secret to aging well.

The gut microbiome refers to the vast collection of microscopic organisms—bacteria, fungi, and viruses—that largely inhabit the colon. These microbes aid in digestion and produce molecules that affect your physiology and psychology. The composition of the microbiome is influenced by a combination of factors, including genetics, diet, the environment, medications, and age.

I’m a microbiology professor and author of “Pleased to Meet Me: Genes, Germs and the Curious Forces That Mak...

In the realm of medical advancements, a universal vaccine that can protect against any pathogen has long been a Holy Grail—and about as elusive as a mythological vessel. But Stanford Medicine researchers and collaborators have taken an astonishing step forward in that quest, surprising even themselves.

In a new study in mice, they have developed a universal vaccine formula that protects against a wide range of respiratory viruses, bacteria and even allergens. The vaccine is delivered intranasally—such as through a nasal spray—and provides broad protection in the lungs for several months.

In the study, published in Sci...

Researchers at UC San Francisco have discovered a mechanism that could explain how exercise improves cognition by shoring up the brain’s protective barrier. With age, the network of blood vessels—called the blood–brain barrier—gets leaky, letting harmful compounds enter the brain. This causes inflammation, which is associated with cognitive decline and is seen in conditions like Alzheimer’s disease. The research is published in the journal Cell.

Six years ago, the team identified a brain-rejuvenating enzyme called GPLD1 that mice produced in their livers when they exercised. But they couldn’t understand how it worked, because it cannot get into the brain.

The new study answers that question...