Category Biology/Biotechnology

Cancer cells proliferate despite a myriad of stresses — from oxygen deprivation to chemotherapy — that would kill any ordinary cell. Now, researchers at UC San Francisco have gained insight into how they may be doing this through the downstream activity of a powerful estrogen receptor. The discovery offers clues to overcoming resistance to therapies like tamoxifen that are used in many types of breast cancer.

Estrogen receptor α (ERα) drives more than 70 percent of breast cancers. The new research published Sept...

Popular diet trend could reduce the risk of diabetes and heart disease. Eating your daily calories within a consistent window of 8-10 hours is a powerful strategy to prevent and manage chronic diseases such as diabetes and heart disease, according to a new manuscript published in the Endocrine Society’s journal, Endocrine Reviews.

Time-restricted eating is a type of intermittent fasting that limits your food intake to a certain number of hours each day. Intermittent fasting is one of the most popular diet trends, and people are using it to lose weight, improve their health and simplify their lifestyles.

“People who are trying to lose weight and live a healthier lifestyle should pay more attention to when they eat as well as what they eat...

Levodopa, or L-dopa, is considered the most effective treatment for Parkinson’s disease today. After a few years of treatment, however, almost all patients develop a debilitating side-effect called L-dopa induced dyskinesia, or LID, which causes involuntary movements in the limbs, face, and torso. Deep brain stimulation can alleviate LID, but the procedure is highly invasive and not all patients are eligible.

Now, a new study led by researchers at the Graduate Center, CUNY and the CUNY School of Medicine shows that drugs that increased signaling by a protein called ...

The EVONANO platform allows scientists to grow virtual tumors and use artificial intelligence to automatically optimize the design of nanoparticles to treat them.

The ability to grow and treat virtual tumors is an important step towards developing new therapies for cancer. Importantly, scientists can use virtual tumors to optimize design of nanoparticle-based drugs before they are tested in the laboratory or patients.

The paper, “Evolutionary computational platform for the automatic discovery of nanocarriers for cancer treatment,” is published today in the Nature journal Computational Materials. The paper is the result of the European project EVONANO which involves Dr...