Category Biology/Biotechnology

Scientists identify first compound to repair degenerating brain cells in paralyzing disease. Northwestern University scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic lateral sclerosis), a swift and fatal neurodegenerative disease that paralyzes its victims.

In addition to ALS, upper motor neuron degeneration also results in other motor neuron diseases, such as hereditary spastic paraplegia (HSP) and primary lateral sclerosis (PLS).

In ALS, movement-initiating nerve cells in the brain (upper motor neurons) and muscle-controlling nerve cells in the spinal cord (lower motor neurons) die. The disease results in rapidly progressing paralysis and death.

So...

3D-printed novel biomaterial mimics properties of living tissues. Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries. And imagine if they could “grow” these neurons in the laboratory from a patient’s own cells using a synthetic, highly bioactive material that is suitable for 3D printing.

By discovering a new printable biomaterial that can mimic properties of brain tissue, Northwestern University researchers are now closer to developing a platform capable of treating these conditions using regenerative medicine.

A key ingredient to the discovery is the ability to control the self-assembly processes of molecules within the m...

Gaia survey provides location and motion of 1.3 million binary pairs within 3,000 light years of Earth. A doctoral student has mined the most recent Gaia survey for all binary stars near Earth and created a 3D atlas of 1.3 million of them. The last local survey included about 200 binary pairs. With such census data, astronomers can conduct statistical analyses on binary populations. For pairs that contain white dwarfs, it’s possible to determine the age of their main-sequence companion, and thus of any exoplanets around them.

The latest star data from the Gaia space observatory has for the first time allowed astronomers to generate a massive 3D atlas of widely separated binary stars within about 3,000 l...

A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.

Studies of humans who live longer than 100 years have shown that many share an unusual version of a gene called Forkhead box protein O3 (FOXO3). That discovery led Dr. Jihye Paik, associate professor of pathology and laboratory medicine at Weill Cornell Medicine, and her colleagues to investigate how this gene contributes to brain health during aging.

In 2018, Dr...