A structural snapshot of a phosphohistidine analogue (ball and stick model) nestled at the interface between different areas (green, brown) of a phosphohistidine antibody. Such structures provide insights into the molecular properties of the antibodies, which makes them useful for revealing elusive phosphohistidine-containing proteins in cells. Credit: Salk Institute
Xray crystallography and recombinant antibodies uncover workings of an elusive molecule central to human health. In structural biology, some molecules are so unusual they can only be captured with a unique set of tools...
Members of NASA’s Perseverance Mars rover team watch in mission control as the first images arrive moments after the spacecraft successfully touched down on Mars, Thursday, Feb. 18, 2021, at NASA’s Jet Propulsion Laboratory in Pasadena, California. A key objective for Perseverance’s mission on Mars is astrobiology, including the search for signs of ancient microbial life. The rover will characterize the planet’s geology and past climate, pave the way for human exploration of the Red Planet, and be the first mission to collect and cache Martian rock and regolith. Credits: NASA/Bill Ingalls
The largest, most advanced rover NASA has sent to another world touched down on Mars Thursday, after a 203-day journey traversing 293 million miles (472 million kilometers)...
According to some estimates, chronic pain affects up to 40% of Americans, and treating it frustrates both clinicians and patients — a frustration that’s often compounded by a hesitation to prescribe opioids for pain.
A new study from the University of Michigan School of Dentistry confirms that a low dose of a drug called naltrexone is a good option for patients with orofacial and chronic pain, without the risk of addiction, said first author Elizabeth Hatfield, a clinical lecturer in the Department of Oral and Maxillofacial Surgery and Hospital Dentistry.
Naltrexone is a semisynthetic opioid first developed in 1963 as an oral alternative to naloxone, the nasal spray used to reverse opioid drug overdoses. When prescribed at doses of 50 to 100 milligrams, naltrexone blocks the effe...
People who eat a Mediterranean-style diet — particularly one rich in green leafy vegetables and low in red meat — are more likely to stay mentally sharp in later life, a study shows.
Closely adhering to a Mediterranean diet was associated with higher scores on a range of memory and thinking tests among adults in their late 70s, the research found.
The study found no link, however, between the Mediterranean-style diet and better brain health. Markers of healthy brain ageing — such as greater grey or white matter volume, or fewer white matter lesions — did not differ between those regularly eating a Mediterranean diet and those who did not.
These latest findings suggest that this primarily plant-based diet may have benefits for cognitive functioning as we get older, researchers...
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