Category Biology/Biotechnology

Sound Waves power New Advances in Drug Delivery and Smart Materials

The patented ‘Respite’ nebuliser uses high-frequency sound waves to precisely deliver drugs to the lungs.
The patented ‘Respite’ nebuliser uses high-frequency sound waves to precisely deliver drugs to the lungs.

Researchers have revealed how high-frequency sound waves can be used to build new materials, make smart nanoparticles and even deliver drugs to the lungs for painless, needle-free vaccinations.

While sound waves have been part of science and medicine for decades — ultrasound was first used for clinical imaging in 1942 and for driving chemical reactions in the 1980s — the technologies have always relied on low frequencies.

Now researchers at RMIT University in Melbourne, Australia, have shown how high frequency sound waves could revolutionise the field of ultrasound-driven chemistry.

A new review published in Advanced Science reveals the bizarre effects of these sound w...

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Therapeutic PD-1 cancer vaccine shown to be safe and effective in animal study

 Identification of four B-cell epitope sequences of human PD-1

First-in-human clinical trial will test vaccine in select cancer patients. A study led by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) described a potential therapeutic anticancer vaccine that frees suppressed cancer-killing immune cells, enabling them to attack and destroy a tumor.

Published in the journal Oncoimmunology, on October 1, 2020, the findings showed that the peptide called PD1-Vaxx, a first checkpoint inhibitor vaccine, was safe and effective in a colon cancer syngeneic animal model.

The vaccine produced polyclonal antibodies that inhibit the programmed cell death receptor, PD-1, on cancer c...

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Gut Immune Cells may help send Multiple Sclerosis into Remission

This shows a head and neurons
The findings confirm for the first time that gut immune cells are involved in MS relapses in humans. Image is in the public domain

An international research team led by UCSF scientists has shown, for the first time, that gut immune cells travel to the brain during multiple sclerosis (MS) flare-ups in patients. These gut cells seem to be playing a protective role, helping drive MS symptoms back into remission.

Scientists know that in MS, other types of immune cells go haywire and attack myelin, crucial insulation material that helps nerve cells communicate with one another quickly and reliably. The resulting damage leads to periodic MS attacks that can leave patients struggling with vision loss, memory problems, pain and other symptoms...

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New Insights into Memristive devices by combining Incipient Ferroelectrics and Graphene

The combination with graphene opens up a new path to memristive heterostructures combining ferroelectric materials and 2D materials. | Illustration Banerjee lab, University of Groningen

Scientists are working on new materials to create neuromorphic computers, with a design based on the human brain. A crucial component is a memristive device, the resistance of which depends on the history of the device — just like the response of our neurons depends on previous input. Materials scientists from the University of Groningen analysed the behaviour of strontium titanium oxide, a platform material for memristor research and used the 2D material graphene to probe it. On 11 November 2020, the results were published in the journal ACS Applied Materials and Interfaces.

Computers are giant calc...

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