Category Biology/Biotechnology

World’s Smallest Ultrasound Detector created

Silicon chip (approx. 3 mm x 6 mm) with multiple detectors. The fine black engravings on the surface of the chip are the photonics circuits interconnecting the detectors (not visible with bare eyes). In the background a larger scale photonics circuit on a silicon wafer. © Helmholtz Zentrum München

Researchers at Helmholtz Zentrum München and the Technical University of Munich (TUM) have developed the world’s smallest ultrasound detector. It is based on miniaturized photonic circuits on top of a silicon chip. With a size 100 times smaller than an average human hair, the new detector can visualize features that are much smaller than previously possible, leading to what is known as super-resolution imaging.

Since the development of medical ultrasound imaging in the 1950s, the co...

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Device could Help Detect Signs of Extraterrestrial Life

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A fully automated microchip electrophoresis analyzer could someday be deployed in the search for life on other worlds.
Credit: Adapted from Analytical Chemistry 2020, DOI: 10.1021/acs.analchem.0c01628

Although Earth is uniquely situated in the solar system to support creatures that call it home, different forms of life could have once existed, or might still exist, on other planets. But finding traces of past or current lifeforms on other worlds is challenging. Now, researchers reporting in ACS’ Analytical Chemistry have developed a fully automated microchip electrophoresis analyzer that, when incorporated into a planetary rover, could someday detect organic biosignatures in extraterrestrial soil.

One critical piece of evidence for life beyond Earth is the presence of certain organic...

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Immune System may have another job—Combatting Depression

Woman with sun behind her and dark clouds in the distance.
(© stock.adobe.com)

An inflammatory autoimmune response within the central nervous system similar to one linked to neurodegenerative diseases such as multiple sclerosis (MS) has also been found in the spinal fluid of healthy people, according to a new Yale-led study comparing immune system cells in the spinal fluid of MS patients and healthy subjects. The research, published Sept. 18 in the journal Science Immunology, suggests these immune cells may play a role other than protecting against microbial invaders—protecting our mental health.

The results buttress an emerging theory that gamma interferons, a type of immune cell that helps induce and modulate a variety of immune system responses, may also play a role in preventing depression in healthy people.

“We were surprised tha...

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Injectable Hydrogel could someday lead to more effective Vaccines

Abstract Image
Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity

Vaccines have curtailed the spread of several infectious diseases, such as smallpox, polio and measles. However, vaccines against some diseases, including HIV-1, influenza and malaria, don’t work very well, and one reason could be the timing of antigen and adjuvant presentation to the immune system. Now, researchers reporting in ACS Central Science developed an injectable hydrogel that allows sustained release of vaccine components, increasing the potency, quality and duration of immune responses in mice.

To confer resistance to infectious diseases, vaccines display parts of a pathogen – known as antigens – to cells of the immune system, which develop antibodies against these molecules...

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