Category Biology/Biotechnology

This discovery may have clinical importance in management of heart failure. Oxidative stress can be pathological. Now researchers report that the other end of the redox spectrum, reductive stress, is also pathological. Reductive stress causes pathological heart enlargement and diastolic dysfunction in a mouse model.

Many heart diseases are linked to oxidative stress, an overabundance of reactive oxygen species. The body reacts to reduce oxidative stress — where the redox teeter-totter has gone too far up — through production of endogenous antioxidants that reduce the reactive oxygen species. This balancing act is called redox homeostasis.

But what happens if the redox teeter-totter goes too far down, crea...

Cappuccino, latte or short black, coffee is one of the most commonly consumed drinks in the world. But whether it’s good or bad for your health can be clarified by genetics, as a world-first study from the University of South Australia’s Australian Centre for Precision Health shows that excess coffee consumption can cause poor health.

Using data from over 300,000 participants in the UK Biobank, researchers examined connections between genetically instrumented habitual coffee consumption and a full ra...

New research could lead to safely reusable PPE. Researchers have created a textile coating that can not only repel liquids like blood and saliva but can also prevent viruses from adhering to the surface. Masks, gowns, and other personal protective equipment (PPE) are essential for protecting healthcare workers. However, the textiles and materials used in such items can absorb and carry viruses and bacteria, inadvertently spreading the disease the wearer sought to contain.

When the coronavirus spread amongst healthcare professionals and left PPE in short supply, finding a way to provide better protection while allowing for the safe reuse of these items became paramount.

Research from the LAMP Lab at the Universit...

Platelets not only play a key role in blood clotting, but can also significantly intensify inflammatory processes. This is shown by a new study carried out by scientists from the University of Bonn together with colleagues from Sao Paulo (Brazil). In the medium term, the results could open up new ways to treat autoimmune diseases. They have now been published in the journal Cell Reports.

For a long time, the role of platelets appeared to be clear: in the event of an injury, they adhere to the wound and stick to each other to rapidly stop the bleeding...