Category Biology/Biotechnology

COVID-19: Stopgap Measure to Treat Respiratory Distress

Researchers from MIT and the University of Colorado at Denver propose using a protein called tissue plasminogen activator, whose structure is shown here, to treat Covid-19 patients in acute respiratory distress.
Image: Wikimedia, MedicineFTWq; edited by MIT News

Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress. By repurposing a drug that is now used to treat blood clots, they believe they could help people in cases where a ventilator is not helping, or if a ventilator is not available.

Three hospitals in Massachusetts and Colorado are developing plans to test this approach in severely ill Covid-19 patients...

Read More

Crumpled Graphene makes Ultra-Sensitive Cancer DNA detector

Illinois researchers found that crumpling graphene in DNA sensors made it tens of thousands of times more sensitive, making it a feasible platform for liquid biopsy. Credit: Mohammad Heiranian

Graphene-based biosensors could usher in an era of liquid biopsy, detecting DNA cancer markers circulating in a patient’s blood or serum. But current designs need a lot of DNA. In a new study, crumpling graphene makes it more than ten thousand times more sensitive to DNA by creating electrical “hot spots,” researchers at the University of Illinois at Urbana-Champaign found.

Crumpled graphene could be used in a wide array of biosensing applications for rapid diagnosis, the researchers said. They published their results in the journal Nature Communications.

“This sensor can detect ultra-low...

Read More

Coronavirus Patients, Doctors seem to be temporarily Losing their sense of Taste and Smell — here’s why

Healthcare workers wait for people to arrive at a COVID-19 mobile testing site in Florida. New reports from the UK show that both doctors and patients with exposure to the coronavirus are temporarily losing their sense of smell and taste. (Photo: Paul Hennessy/NurPhoto via Getty Images)

As COVID-19 continues to spread, now topping 370,000 cases worldwide, mentions of a previously unknown symptom of COVID-19 — loss of smell — are gaining traction. “Haven’t been able to smell anything for the last 4 days,” tweeted Rudy Gobert, a player of the Utah Jazz who was the first NBA player to test positive for the coronavirus 11 days ago. “Anyone experiencing the same thing?

According to a paper published Friday by Claire Hopkins, PhD, a professor of rhinology at King’s College Londo...

Read More

A doctor is 3D-Printing Face Masks to help meet the desperate need for protective gear + A NY couple is printing 100s of Face Shields

The plastic mask uses a small square of a surgical mask as a filter.
The plastic mask uses a small square of a surgical mask as a filter.

In Billings, Montana, some healthcare professionals are using 3D printers to make reusable plastic face masks. The masks are then fitted with pieces of surgical masks which can be swapped out as needed.

The surgical masks are cut into smaller squares that can be clipped into the plastic mask to serve as a filter, Dusty Richardson, a neurosurgeon at the Billings Clinic told CNN.
“The filter can be used for a day and you can change it out the next day, but I do wash my mask out frequently,” Richardson said.

The plastic can be cleaned with soap and water, bleach and other disinfecting products. Richardson estimates healthcare workers can get 6 to 10 uses out of a single surgical mask...

Read More