Category Biology/Biotechnology

New Research Sheds Light on Potentially Negative Effects of Cannabis

 Overbaked: assessing and predicting acute adverse reactions to CannabisJournal of Cannabis Research, 2020; 2 (1) DOI: 10.1186/s42238-019-0013-x

Coughing fits, anxiety and paranoia are three of the most common adverse reactions to cannabis, according to a recent study by Washington State University researchers. They surveyed > 1,500 college students on the type and frequency of adverse reactions they had experienced while using cannabis for their study in the Journal of Cannabis Research. They also collected information on the students’ demographics, personality traits, cannabis use patterns and motives for using the drug.

“There’s been surprisingly little research on the prevalence or frequency of various adverse reactions to cannabis and almost no research trying to predict wh...

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Reusable Respirators may be a suitable Alternative to Disposable Respirators

A reusable respirator on a table
credit: NIOSH / CDC
A reusable respirator.

Researchers have found that reusable respirators may be a suitable alternative to disposable N95 respirators currently in high demand. Shortages of respiratory protective devices for healthcare personnel are major concerns during the COVID-19 pandemic. A team of researchers at Baylor College of Medicine, Emory University, the University of Texas Health Science Center at Houston and the National Institute for Occupational Safety and Health Centers at the Centers for Disease Control and Prevention have found that reusable respirators may be a suitable alternative to disposable N95 respirators currently in high demand. The study appears in the journal JAMA.

“Training and fit testing healthcare providers on respirators can be time consuming, a...

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How Trans Fats Assist Cell Death

Trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop
Authors: Yusuke Hirata, Aya Inoue, Saki Suzuki, Miki Takahashi, Ryo Matsui, Nozomu Kono, Takuya Noguchi, and Atsushi Matsuzawa
Journal: Scientific Reports
DOI: https://doi.org/10.1038/s41598-020-59636-6

Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases. Their findings, published in the journal Scientific Reports, implicate their role in enhancing a mitochondrial signalling pathway that leads to programmed cell death.

“Accumulating evidence has associated the consumption of trans-fatty acids with various diseases, including some lifestyle d...

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COVID-19: Stopgap Measure to Treat Respiratory Distress

Researchers from MIT and the University of Colorado at Denver propose using a protein called tissue plasminogen activator, whose structure is shown here, to treat Covid-19 patients in acute respiratory distress.
Image: Wikimedia, MedicineFTWq; edited by MIT News

Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress. By repurposing a drug that is now used to treat blood clots, they believe they could help people in cases where a ventilator is not helping, or if a ventilator is not available.

Three hospitals in Massachusetts and Colorado are developing plans to test this approach in severely ill Covid-19 patients...

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