Category Biology/Biotechnology

Identical Mice, different Gut Bacteria, different Levels of Cancer

Photo of researcher suited up holding tank with mouse inside.
Photo courtesy of ULAM Germ-Free Mouse Facility.

Researchers at the University of Michigan Rogel Cancer Center are shedding new light on the way microorganisms that live in the gastrointestinal tract can affect the development of colorectal cancer.

Some types of gut bacteria are better than others at stimulating certain immune cells, specifically CD8+ T cells, in the body, they found. And while these CD8+ T cells normally help protect the body against cancer, overstimulating them may promote inflammation and exhaust the T cells — which can actually increase susceptibility to cancer, according to new mouse model study published in Cell Reports.

The work will help scientists pinpoint which populations of bacteria are tumor suppressive or tumor promoting and how, says study first au...

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Now Metal Surfaces can be Instant Bacteria Killers

A laser prepares to texture the surface of copper, enhancing its antimicrobial properties. (Purdue University photo/Kayla Wiles)

Bacterial pathogens can live on surfaces for days. What if frequently touched surfaces such as doorknobs could instantly kill them off?

Purdue University engineers have created a laser treatment method that could potentially turn any metal surface into a rapid bacteria killer – just by giving the metal’s surface a different texture.

In a study published in the journal Advanced Materials Interfaces, the researchers demonstrated that this technique allows the surface of copper to immediately kill off superbugs such as MRSA.

“Copper has been used as an antimicrobial material for centuries...

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How Silver Ions Kill Bacteria

 Silver Ions Caused Faster Diffusive Dynamics of Histone-Like Nucleoid-Structuring Proteins in Live Bacteria. Applied and Environmental Microbiology, 2020; 86 (6) DOI: 10.1128/AEM.02479-19

The antimicrobial properties of silver have been known for centuries. While it is still a mystery as to exactly how silver kills bacteria, University of Arkansas researchers have taken a step toward better understanding the process by looking at dynamics of proteins in live bacteria at the molecular level.

Traditionally, the antimicrobial effects of silver have been measured through bioassays, which compare the effect of a substance on a test organism against a standard, untreated preparation...

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Where in the Brain does Creativity come from? Evidence from Jazz Musicians

Brain activity maps showing areas associated with high-creativity performances compared with lower-creativity performances. Each map shows a top view of the head.

A new brain-imaging study has studied the brain activity of jazz guitarists during improvisation to show that creativity is, in fact, driven primarily by the right hemisphere in musicians who are comparatively inexperienced at improvisation. However, musicians who are highly experienced at improvisation rely primarily on their left hemisphere.

This suggests that creativity is a “right-brain ability” when a person deals with an unfamiliar situation but that creativity draws on well-learned, left-hemisphere routines when a person is experienced at the task.

By taking into consideration how brain activity changes with expe...

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