Category Biology/Biotechnology

Novel Coronavirus Receptors show similarities to SARS-CoV, according to new analysis

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Previous studies have shown how the SARS virus (SARS-CoV) interacts with animal and human hosts in order to infect them. The mechanics of infection by the Wuhan coronavirus appear to be similar.

The recent emergence of Wuhan coronavirus (2019-nCoV) has put the world on high alert for transcontinental transmission, reminiscent of the outbreak of SARS – also a coronavirus – in 2002-2003.

Decade-long structural studies by Fang Li of the University of Minnesota, et al. have shown how the SARS virus (SARS-CoV) interacts with animal and human hosts in order to infect them. The mechanics of infection by the Wuhan coronavirus appear to be similar...

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Gut reaction: How Immunity ramps up against Incoming Threats

Image result for VIP directly regulates IL-22 production by ILC3s.
ILC2 and ILC3 activities oscillate during the active and resting phase at steady state in wild-type mice.

A new study has revealed how the gut’s protective mechanisms ramp up significantly with food intake, and at times of the day when mealtimes are anticipated based on regular eating habits.

Researchers from the Walter and Eliza Hall Institute found, in laboratory models, that eating sets off a hormonal ‘chain reaction’ in the gut.

Eating causes a hormone called VIP to kickstart the activity of immune cells in response to potentially incoming pathogens or ‘bad’ bacteria. The researchers also found that immunity increased at anticipated mealtimes indicating that maintaining regular eating patterns could be more important than previously thought.

With the rise in conditions a...

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Nanoparticle Chomps away Plaques that cause Heart Attacks

The dotted line outlines the atherosclerotic artery and the green represents our nanoparticles, which are in the plaque. The red indicates macrophages, which is the cell type that the nanoparticles are stimulating to eat the debris.

Michigan State University and Stanford University scientists have invented a nanoparticle that eats away – from the inside out – portions of plaques that cause heart attacks.

Bryan Smith, associate professor of biomedical engineering at MSU, and a team of scientists created a “Trojan Horse” nanoparticle that can be directed to eat debris, reducing and stabilizing plaque. The discovery could be a potential treatment for atherosclerosis, a leading cause of death in the United States.

The results, published in the current issue of Nature Nanotechno...

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Parkinson’s Disease may start Before Birth

Clive Svendsen, PhD, director of the Cedars-Sinai Board of Governors Regenerative Medicine Institute, right, and Nur Yucer, PhD, a project scientist, discuss a microscope image of dopamine neurons. Photo by Cedars-Sinai.

Stem cell study finds malfunctioning brain cells in patients who were diagnosed before age 50; researchers test potential new treatment. People who develop Parkinson’s disease before age 50 may have been born with disordered brain cells that went undetected for decades, according to new Cedars-Sinai research. The research points to a drug that potentially might help correct these disease processes.

Parkinson’s occurs when brain neurons that make dopamine, a substance that helps coordinate muscle movement, become impaired or die...

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