Category Biology/Biotechnology

Synthetic Biology used to Target Cancer Cells while Sparing Healthy Tissue

(Top) some types of cancers are caused by mutated or overexpressed cell surface proteins that signal to the nucleus (green pathway) to drive uncontrolled growth and survival. (Bottom) Using an approach called RASER, the cancer-causing signals are redirected away from cell growth and survival and toward programmed cell death (orange pathway).
Michael Lin and Stuart Jantzen

Synthetic proteins engineered to recognize overly active biological pathways can kill cancer cells while sparing their healthy peers, according to a study by researchers at the Stanford University School of Medicine...

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Walnuts may help Lower Blood Pressure for those at risk of Heart Disease

open walnut with heart
Penny Kris-Etherton, distinguished professor of nutrition at Penn State, said the study suggests that because walnuts lowered central pressure, the participants’ risk of CVD may also have decreased.IMAGE: © GETTY IMAGES / CALYPSOART

When combined with a diet low in saturated fats, eating walnuts may help lower blood pressure in people at risk for cardiovascular disease, according to a new Penn State study.

In a randomized, controlled trial, researchers examined the effects of replacing some of the saturated fats in participants’ diets with walnuts. They found that when participants ate whole walnuts daily in combination with lower overall amounts of saturated fat, they had lower central blood pressure.

According to the researchers, central pressure is the pressure that is exer...

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Put down the Protein Shake: Variety of protein better for health

protein shake
Samantha M. Solon-Biet et al, Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control, Nature Metabolism (2019). DOI: 10.1038/s42255-019-0059-2

Popular protein great for increasing muscle mass, but could reduce your life-span – researchers say to vary protein intake. Researchers have examined whether there are any ongoing ramifications or potential side-effects from long-term high protein intake or from consuming certain types of amino acids.

Led by academics from the University of Sydney’s Charles Perkins Centre, Professor Stephen Simpson and Dr Samantha Solon-Biet, suggests that while delivering muscle-building benefits, excessive consumption of branched-chain amino acids (BCAAs) may reduce lifespan, negatively impact mood and...

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Urine Test could prevent Cervical Cancer, study finds

A comparison of the mean ct values for detection of the internal beta globin control and HR-HPV in urine, vaginal and cervical samples using the ART (A,B) and RC assays (C,D). ct, cycle threshold; HPV, human papillomavirus. 

Urine testing may be as effective as the smear test at preventing cervical cancer, according to new research by University of Manchester scientists. The study, led by Dr Emma Crosbie and published in BMJ Open, found that urine testing was just as good as the cervical smear at picking up high-risk human papillomavirus (HPV), the virus that causes cervical cancer.

The research team say a urine test could help increase the numbers of women who are screened for cervical cancer, which affects more than 3,000 women every year in the UK.
Urine testing could also have...

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