Category Biology/Biotechnology

Fasting Ramps up Human Metabolism, study shows

A study by the G0 Cell Unit and Kyoto University researchers suggests that fasting, which puts the body in ‘starvation mode,’ leads to fuel substitution, antioxidation, increased mitochondrial activation and altered signal transduction.
Credit: OIST

Fasting may help people lose weight, but new research suggests going without food may also boost human metabolic activity, generate antioxidants, and help reverse some effects of aging. Scientists at the Okinawa Institute of Science and Technology Graduate University (OIST) and Kyoto University identified 30 previously-unreported substances whose quantity increases during fasting and indicate a variety of health benefits.

“We have been researching aging and metabolism for many years and decided to search for unknown health effects in human ...

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Engineers Translate Brain Signals directly into Speech

Figure 1

Schematic of the speech reconstruction method.

Advance marks critical step toward brain-computer interfaces that hold immense promise for those with limited or no ability to speak. In a scientific first, Columbia neuroengineers have created a system that translates thought into intelligible, recognizable speech. By monitoring someone’s brain activity, the technology can reconstruct the words a person hears with unprecedented clarity. This breakthrough, which harnesses the power of speech synthesizers and artificial intelligence, could lead to new ways for computers to communicate directly with the brain...

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Cancer: A Mutation that Breaks Gene Interplay in 3D

An illustration of chromatin contacts in the cell nucleus that activate transcription.
Credit: Giovanni Ciriello (UNIL)

Scientists have discovered how a mutated gene can affect the three-dimensional interactions of genes in the cell, leading to various forms of cancer. Inside the cell, DNA is tightly wrapped around proteins and packed in a complex, 3D structure that we call “chromatin.” Chromatin not only protects our genetic material from damage, but also organizes the entire genome by regulating the expression of genes in three dimensions, unwinding them to be presented to the cell’s gene-expression machinery and then winding them back in.

Inside the 3D chromatin structure there are certain regions called “topologically associating domains” or TADs...

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Not all Saturated Fats are equal when it comes to Heart Health

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Consumption of individual saturated fatty acids and the risk of myocardial infarction in a UK and a Danish cohortInternational Journal of Cardiology, 2018; DOI: 10.1016/j.ijcard.2018.10.064
Jun Li, Qi Sun. Consumption of saturated fatty acids and coronary heart disease riskInternational Journal of Cardiology, 2019; DOI: 10.1016/j.ijcard.2019.01.022

Cardiovascular risk of diets rich in saturated fats found in meats and the benefits of plant-based and dairy alternatives. The type of saturated fats we eat can affect our risk of a heart attack, according to a study published in the International Journal of Cardiology...

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