Category Biology/Biotechnology

Stroke triggers a hidden brain change that looks like rejuvenation

Stroke May Rejuvenate the Brain
When a stroke damages brain tissue along an important movement pathway, the injured side of the brain may show faster aging (red), while parts of the opposite side may appear relatively “younger” (blue) as the brain tries to compensate. This pattern is linked to more severe movement problems and less recovery. Credit: Stevens INI

Stroke may secretly “rejuvenate” parts of the brain as it fights to recover.
After a stroke, the brain may do something surprisingly hopeful—it can “refresh” parts of itself. Researchers analyzing brain scans from over 500 stroke survivors found that while the damaged side of the brain appears to age faster, the opposite, unaffected side can actually look younger...

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Implantable islet cells could control diabetes without insulin injections

Two tiny rectangular devices have curved edges. The devices are orange-yellow and are made of a circuit board and soldered pieces, including a diamond-shaped piece of material in the middle.
Caption:MIT engineers designed an implantable device that carries hundreds of thousands of islet cells along with its own on-board oxygen factory to keep the cells healthy.
Credits:Image: Felice Frankel

Most diabetes patients must carefully monitor their blood sugar levels and inject insulin multiple times per day, to help keep their blood sugar from getting too high. As a possible alternative to those injections, MIT researchers are developing an implantable device that contains insulin-producing cells. The device encapsulates the cells, protecting them from immune rejection, and it also carries an onboard oxygen generator to keep the cells healthy.

This device, the researchers hope, could offer a way to achieve long-term control of type 1 diabetes...

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Could a gut microbe influence muscle strength?

The trillions of microbes living in the human gut are increasingly recognized as important partners in human health. Scientists have linked the gut microbiome to several aspects of health, from metabolism and immunity to mental health.

A recent study suggests that these microbes may also influence an important aspect of fitness—muscle strength.

Muscle strength is a crucial feature of health for many reasons. It supports our joints and keeps our bones healthy, boosts athletic performance and even plays a role in metabolic health.

Muscle strength also helps us maintain independence later in life. As muscles gradually weaken as we get older, everyday tasks become harder and the risk of falls increases...

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Key protein found to protect cartilage, offering new hope for osteoarthritis treatment

SHP protein found to protect cartilage, offering new hope for osteoarthritis treatment
Schematic illustration of SHP (NR0B2)-mediated protection against osteoarthritis. Credit: Korea Research Institute of Bioscience and Biotechnology (KRIBB)

Osteoarthritis, a condition that causes pain and reduced mobility in joints such as the knees and fingers, is one of the most common joint disorders worldwide, particularly among aging populations. The disease is characterized by the gradual breakdown of cartilage, which normally cushions the bones within joints.

Despite its prevalence, current treatments for osteoarthritis mainly focus on alleviating pain rather than addressing the underlying cause of cartilage degeneration. Effective therapies that can halt or reverse cartilage damage remain limited.

A joint research team led by Dr. Chul-Ho Lee and Dr...

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