Category Biology/Biotechnology

Brown University researchers have created a hybrid material out of seaweed-derived alginate and the nanomaterial graphene oxide. The 3-D printing technique used to make the material enables the creation of intricate structures, including the one above, which mimics that atomic lattice a graphene.
Credit: Wong Lab / Brow University

Brown University researchers have shown a way to use graphene oxide (GO) to add some backbone to hydrogel materials made from alginate, a natural material derived from seaweed that’s currently used in a variety of biomedical applications. In a paper published in the journal Carbon, the researchers describe a 3D printing method for making intricate and durable alginate-GO structures that are far stiffer and more fracture resistant that alginate alone.

“One limiting...

Electron microscope image of the porous hydrogel. Credit: UNH

Wound healing can be complex and challenging, especially when a patient has other health obstacles that seriously impede the process. Often injectable hydrogels are applied to irregular shaped wounds, like diabetic ulcers, to help form a temporary matrix, or structure, to keep the wound stable while cells rejuvenate. The caveat is that current hydrogels are not porous enough and do not allow neighboring cells to pass through toward the wound to help it mend.

“While valuable for helping patients, current hydrogels have limited clinical efficacy,” said Kyung Jae Jeong, assistant professor of chemical engineering at UNH. “We discovered a simple solution to make the hydrogels more porous and therefore help to speed up the healing...

A new shoe insole technology could help diabetic ulcers heal better while walking.
Credit: Purdue University image/Kayla Wiles

Researchers have developed a shoe insole that could help make the healing process more portable for the 15 percent of Americans who develop ulcers as a result of diabetes.
Diabetes can lead to ulcers that patients don’t even feel or notice until the sight of blood. And because ulcers can’t heal on their own, 14 to 24% of diabetics in the U.S. who experience them end up losing their toes, foot or leg.

Purdue University researchers have developed a shoe insole that could help make the healing process more portable for the 15 percent of Americans who develop ulcers as a result of diabetes...

M Makrides, L Duley, SF Olsen. Fish oil and other prostaglandin precursor supplementation during pregnancy for reducing pre-eclampsia, preterm birth, low birth weight and intrauterine growth restriction. Cochrane Review, 2018 DOI: http://dx.doi.org/10.1002/14651858.CD003402

A new Cochrane Review published today has found that increasing the intake of omega-3 long-chain polyunsaturated fatty acids (LCPUFA) during pregnancy reduces the risk of premature births. Premature birth is the leading cause of death for children under 5 years old worldwide, accounting for close to one million deaths annually. Premature babies are at higher risk of a range of long-term conditions including visual impairment, developmental delay and learning difficulties.

“We know premature birth is a critical global he...