Category Biology/Biotechnology

How Exercise Reduces Belly Fat in humans

This graphical abstract shows that in abdominally obese people, exercise-mediated loss of visceral adipose tissue mass requires IL-6 receptor signaling.
CREDIT
Wedell-Neergaard, Lehrskov, and Christensen, et al. / Cell Metabolism

Some of you may have made a New Year’s resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 plays a critical role in this process, researchers report December 27 in the journal Cell Metabolism.

As expected, a 12-week intervention consisting of bicycle exercise decreased visceral abdominal fat in obese adults...

Read More

Sustainable ‘Plastics’ are on the Horizon


Macroalgal biomass subcritical hydrolysates for the production of polyhydroxyalkanoate (PHA) by Haloferax mediterranei

New sustainable biopolymer technology may one day free the world of its worst pollutant. A new Tel Aviv University study describes a process to make bioplastic polymers that don’t require land or fresh water – resources that are scarce in much of the world. The polymer is derived from microorganisms that feed on seaweed. It is biodegradable, produces zero toxic waste and recycles into organic waste.

The invention was the fruit of a multidisciplinary collaboration between Dr. Alexander Golberg of TAU’s Porter School of Environmental and Earth Sciences and Prof. Michael Gozin of TAU’s School of Chemistry...

Read More

Salk Scientists find Genetic Signatures of Biological Aging

Fig. 1

Predicting age from gene expression data. Rows from top to bottom show age prediction results for LDA Ensemble with 20-year age bins, elastic net, linear regression, and support vector regression

Some people appear to be considerably younger or older than their chronological age. Genetic signatures that may help explain this have been discovered by scientists at the Salk Institute. The age-associated genetic patterns were found by analyzing skin cells from people of various ages, according to a study by Salk Institute scientists.

Researchers then applied the results to detect genetic signs of accelerated aging in people with progeria, a disease that causes patients to appear far older than their chronological age...

Read More

Human Blood Cells can be directly Reprogrammed into Neural stem cells


Stem cells are considered to be the all-rounders of our tissues: they can multiply indefinitely and then — if they are pluripotent embryonic stem cells — generate all conceivable cell types.
Credit: © M.C. Thier/DKFZ

Scientists from the German Cancer Research Center (DKFZ) and the stem cell institute HI-STEM* in Heidelberg have succeeded for the first time in directly reprogramming human blood cells into a previously unknown type of neural stem cell. These induced stem cells are similar to those that occur during the early embryonic development of the central nervous system. They can be modified and multiplied indefinitely in the culture dish and can represent an important basis for the development of regenerative therapies.

Stem cells are considered to be the all-rounders of our tiss...

Read More