Category Biology/Biotechnology

UCI researchers uncover evidence of Restored Vision in rats following Cell Transplant

The left side of the figure illustrates the retina transplantation procedure. The right side of the figure represents examples of orientation tuning curves recorded from three rats: a normal rat, a rat with a transplant and a rat with a degenerated retina (blind). Displayed below the tuning curves are the responses to sinusoidal grating stimuli. The response patterns indicate that neurons in the brains of transplant recipients are very similar to those of the rats with normal vision.

The left side of the figure illustrates the retina transplantation procedure. The right side of the figure represents examples of orientation tuning curves recorded from three rats: a normal rat, a rat with a transplant and a rat with a degenerated retina (blind). Displayed below the tuning curves are the responses to sinusoidal grating stimuli. The response patterns indicate that neurons in the brains of transplant recipients are very similar to those of the rats with normal vision.

Researchers from the University of California, Irvine School of Medicine, have discovered that neurons located in the vision centers of the brains of blind rats functioned normally following fetal retina cell transplants, indicating the successful restoration of vision...

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Family Tree of 400 million people shows Genetics has Limited Influence on Longevity

Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating. Genetics, 2018; 210 (3): 1109 DOI: 10.1534/genetics.118.301613

Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating. Genetics, 2018; 210 (3): 1109 DOI: 10.1534/genetics.118.301613

Study of huge Ancestry.com pedigree set suggests similar life spans between spouses may have inflated previous estimates of life span heritability. Although long life tends to run in families, genetics has far less influence on life span than previously thought, according to a new analysis of an aggregated set of family trees of more than 400 million people. The results suggest that the heritability of life span is well below past estimates, which failed to account for our tendency to select partners with similar traits to our own...

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New Epilepsy warning device could save thousands of Lives

Nightwatch bracelet on the arm of a young epilepsy patient.
Credit: LivAssured

A new high-tech bracelet, developed by scientists from the Netherlands detects 85% of all severe night-time epilepsy seizures. That is a much better score than any other technology currently available. The researchers involved think that this bracelet, called Nightwatch, can reduce the worldwide number of unexpected night-time fatalities in epilepsy patients. They published the results of a prospective trial in the scientific journal Neurology.

SUDEP, sudden unexpected death in epilepsy, is a major cause of mortality in epilepsy patients. People with an intellectual disability and severe therapy resistant epilepsy, may even have a 20% lifetime risk of dying from epilepsy...

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To ward off Fatty Liver, Breast is Best for Mom

Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women. Journal of Hepatology, 2018; DOI: 10.1016/j.jhep.2018.09.013

Study finds fatty liver disease is less likely to occur in mothers who breastfeed for more than six months. Researchers at University of California San Diego School of Medicine and Kaiser Permanente have discovered that mothers who breastfed a child or children for six months or more are at lower risk for developing non-alcoholic fatty liver disease (NAFLD) years later during mid-life. With no other current prevention options aside from a healthy lifestyle, they say the finding may represent an early modifiable risk factor for a serious and chronic disease.

The findings are published in the November 1 issue of the Jour...

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