Category Biology/Biotechnology

To Improve Auto Coatings, New Tests do more than Scratch the Surface

Photomicrograph showing the result of a NIST nanoscale scratch test on a sample of automobile clearcoat material. The scratch, which shows fractures radiating from the line of impact, is 20 micrometers wide, 150 micrometers long and 2 micrometers deep (A micrometer is a millionth of a meter or about half the length of an average E. coli bacterium.). Credit: NIST

Photomicrograph showing the result of a NIST nanoscale scratch test on a sample of automobile clearcoat material. The scratch, which shows fractures radiating from the line of impact, is 20 micrometers wide, 150 micrometers long and 2 micrometers deep (A micrometer is a millionth of a meter or about half the length of an average E. coli bacterium.).
Credit: NIST

Data from new suite of tests could eventually help your vehicle’s exterior better defend itself against dings, dents, scratches and things that go bump on the highway...

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Intestines Modify their Cellular Structure in Response to Diet

This is a fruit fly. Credit: Carnegie Institution for Science

This is a fruit fly.
Credit: Carnegie Institution for Science

Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility, according to Carnegie’s Rebecca Obniski, Matthew Sieber, and Allan Spradling. Their work, published by Developmental Cell, used fruit flies, which are currently the most-sensitive experimental system for such detecting diet-induced cellular changes that are likely to be similar in mammals.

There are 3 major types of cells in fruit fly (and mammalian) intestines: Stem cells, hormone-producing cells, and nutrient-handling cells...

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Zombie Cells found in Brains of Mice prior to Cognitive Loss

Senescent cells (represented here in green) no longer function but can broadcast inflammatory signals to the cells around them. These cells are implicated in a number of age-related diseases. Credit: Image courtesy of Mayo Clinic

Senescent cells (represented here in green) no longer function but can broadcast inflammatory signals to the cells around them. These cells are implicated in a number of age-related diseases.
Credit: Image courtesy of Mayo Clinic

Zombie cells are the ones that can’t die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, Mayo Clinic researchers have expanded that list.

In a mouse model of brain disease, scientists report that senescent cells accumulate in certain brain cells prior to cognitive loss. By preventing the accumulation of these cells, they were able to diminish tau protein aggregation, neuronal death and memory loss.

“Senescent cells are known to ac...

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Hardwired for Laziness? Tests show the Human Brain must Work Hard to Avoid Sloth

The researchers asked volunteers to react to simple stick drawings depicting scenes of physical inactivity and physical activity, and discovered that brain activity differed depending on the scene. Credit: UBC Media Relations

The researchers asked volunteers to react to simple stick drawings depicting scenes of physical inactivity and physical activity, and discovered that brain activity differed depending on the scene.
Credit: UBC Media Relations

Society has encouraged people to be more physically active, yet we are actually becoming less active. This new study offers a possible explanation: Our brains may be innately attracted to sedentary behavior. Electroencephalograms showed that test subjects had to summon extra brain resources when trying to avoid physical inactivity.

If getting to the gym seems like a struggle, a University of British Columbia researcher wants you to know this: the struggle is real, and it’s happening inside your brain...

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