Category Biology/Biotechnology

Secret Tunnels Discovered between the Skull and the Brain

Newly discovered channels in the skull may provide a shortcut for immune cells going to damaged tissue. Credit: Nahrendorf Lab

Newly discovered channels in the skull may provide a shortcut for immune cells going to damaged tissue. Credit: Nahrendorf Lab

Study suggests immune cells rush through channels to get to injured tissue quickly. Bone marrow, the spongy tissue inside most of our bones, produces red blood cells as well as immune cells that help fight off infections and heal injuries. According to a new study of mice and humans, tiny tunnels run from skull bone marrow to the lining of the brain and may provide a direct route for immune cells responding to injuries caused by stroke and other brain disorders. The study was funded in part by the National Institutes of Health and published in Nature Neuroscience.

“We always thought that immune cells from our arms and legs traveled via blood to damaged brain tissue...

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Scientists Identify a New Kind of Human Brain Cell

This is a digital reconstruction of a rosehip neuron in the human brain. Credit: Tamas Lab, University of Szeged

This is a digital reconstruction of a rosehip neuron in the human brain. Credit: Tamas Lab, University of Szeged

‘Rosehip’ neurons not found in rodents, may be involved in fine-level control between regions of the human brain. One of the most intriguing questions about the human brain is also one of the most difficult for neuroscientists to answer: What sets our brains apart from those of other animals? “We really don’t understand what makes the human brain special,” said Ed Lein, Ph.D., Investigator at the Allen Institute for Brain Science. “Studying the differences at the level of cells and circuits is a good place to start, and now we have new tools to do just that.”

In a new study published today in the journal Nature Neuroscience, Lein and his colleagues reveal one possible answer to ...

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Genetically Engineered Virus Spins Gold into Beads

Electron microscope image of M13 spheroid-templated spiky gold nanobead with corresponding graphical illustration. Credit: Haberer Lab, UC Riverside

Electron microscope image of M13 spheroid-templated spiky gold nanobead with corresponding graphical illustration. Credit: Haberer Lab, UC Riverside

Engineers at the University of California, Riverside, have altered a virus to arrange gold atoms into spheroids measuring a few nanometers in diameter. The finding could make production of some electronic components cheaper, easier, and faster. “Nature has been assembling complex, highly organized nanostructures for millennia with precision and specificity far superior to the most advanced technological approaches,” said Elaine Haberer, a professor of electrical and computer engineering in UCR’s Marlin and Rosemary Bourns College of Engineering and senior author of the paper describing the breakthrough...

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Alzheimer’s One Day may be Predicted during Eye Exam

Greg Van Stavern, MD, (seated) and Rajendra Apte, MD, PhD, examine Kathleen Eisterhold's eyes, using technology that one day may make it possible to screen patients for Alzheimer's disease during an eye exam. In a small study, the eye test was able to detect the presence of Alzheimer's damage in older patients with no symptoms of the disease. Credit: Matt Miller

Greg Van Stavern, MD, (seated) and Rajendra Apte, MD, PhD, examine Kathleen Eisterhold’s eyes, using technology that one day may make it possible to screen patients for Alzheimer’s disease during an eye exam. In a small study, the eye test was able to detect the presence of Alzheimer’s damage in older patients with no symptoms of the disease.
Credit: Matt Miller

Noninvasive test may screen for disease before symptoms appear. It may be possible in the future to screen patients for Alzheimer’s disease using an eye exam. Using technology similar to what is found in many eye doctors’ offices, researchers at Washington University School of Medicine in St. Louis have detected evidence suggesting Alzheimer’s in older patients who had no symptoms of the disease.

Their study, involving 30 patients, ...

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