Category Biology/Biotechnology

Lung-on-a-Chip Simulates Pulmonary Fibrosis

The image above shows collagen from a healthy engineered lung tissue. Credit: Ruogang Zhao

The image above shows collagen from a healthy engineered lung tissue. Credit: Ruogang Zhao

New biotech could reduce time and cost of developing medicine for deadly lung disease. The innovation, lung-on-a-chip technology, relies on the same technology used to print electronic chips, photolithography. Only instead of semiconducting materials, researchers placed upon the chip arrays of thin, pliable lab-grown lung tissues – in other words, its lung-on-a-chip technology.

“Obviously it’s not an entire lung, but the technology can mimic the damaging effects of lung fibrosis...

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Bursts of Brain Activity Linked to Memory Reactivation

Pre-cue Spindles Prevented Post-cue Spindle Increases and Negatively Predicted Memory Retention

Pre-cue Spindles Prevented Post-cue Spindle Increases and Negatively Predicted Memory Retention

Sleep spindles may help memory storage keep memories separate. Leading theories propose that sleep presents an opportune time for important, new memories to become stabilized. And it’s long been known which brain waves are produced during sleep. But in a new study, researchers set out to better understand the brain mechanisms that secure memory storage.

The team from Northwestern and Princeton universities set out to find more direct and precisely timed evidence for the involvement of one particular sleep wave – known as the “sleep spindle.” In the study, sleep spindles, described as bursts of brain activity typically lasting around one second, were linked to memory reactivation...

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Tick Bite Protection: New CDC study adds to the promise of Permethrin-treated Clothing

In a series of experiments conducted by researchers at the US Centers for Disease Control and Prevention, clothing treated with an insecticide known as permethrin had strong toxic effects on three primary species of ticks known to spread disease-causing pathogens in the United States (shown here, left to right): the blacklegged tick (Ixodes scapularis), lone star tick (Amblyomma americanum), and American dog tick (Dermacentor variabilis). Exposure to permethrin interfered with the ticks' ability to move properly, making them sluggish and likely interfering with their ability to bite.

In a series of experiments conducted by researchers at the US Centers for Disease Control and Prevention, clothing treated with an insecticide known as permethrin had strong toxic effects on three primary species of ticks known to spread disease-causing pathogens in the United States (shown here, left to right): the blacklegged tick (Ixodes scapularis), lone star tick (Amblyomma americanum), and American dog tick (Dermacentor variabilis). Exposure to permethrin interfered with the ticks’ ability to move properly, making them sluggish and likely interfering with their ability to bite.

Lab tests show germ-carrying ticks can’t move properly after contact with treated garments. The case for permethrin-treated clothing to prevent tick bites keeps getting stronger...

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Ingestible ‘Bacteria on a Chip’ could help Diagnose Disease

MIT engineers have designed an ingestible sensor equipped with bacteria programmed to sense environmental conditions and relay the information to an electronic circuit. Credit: Lillie Paquette/MIT

MIT engineers have designed an ingestible sensor equipped with bacteria programmed to sense environmental conditions and relay the information to an electronic circuit. Credit: Lillie Paquette/MIT

Ultra-low-power sensors carrying genetically engineered bacteria can detect gastric bleeding or other gastrointestinal problems. This “bacteria-on-a-chip” approach combines sensors made from living cells with ultra-low-power electronics that convert the bacterial response into a wireless signal that can be read by a smartphone...

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