Category Biology/Biotechnology

Eggs not linked to Cardiovascular Risk, despite conflicting advice

Boiled eggs

Boiled eggs Image: Pixabay

No extra risk for people with pre-diabetes or type 2 diabetes. University of Sydney researchers aim to help clear up conflicting dietary advice around egg consumption, as a new study finds eating up to 12 eggs per week for a year did not increase cardiovascular risk factors in people with pre-diabetes and type 2 diabetes.

Published in the American Journal of Clinical Nutrition, the research extends on a previous study that found similar results over a period of three months. Led by Dr Nick Fuller from the University’s Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders at the Charles Perkins Centre, the research was conducted with the University of Sydney’s Sydney Medical School and the Royal Prince Alfred Hospital.

In the initial trial, particip...

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New CRISPR Technology ‘Knocks Out’ Yeast Genes with Single-Point Precision

Image result for : CHAnGE enables rapid generation of genome-wide yeast disruption mutants and directed evolution of complex phenotypes.

CHAnGE enables rapid generation of genome-wide yeast disruption mutants and directed evolution of complex phenotypes.

The CRISPR-Cas9 system has given researchers the power to precisely edit selected genes. Now, researchers have used it to develop a technology that can target any gene in the yeast Saccharomyces cerevisiae and turn it off by deleting single letters from its DNA sequence. Such genome-scale engineering – in contrast to traditional strategies that only target a single gene or a limited number of genes – allows researchers to study the role of each gene individually, as well as in combination with other genes. It also could be useful for industry, where S. cerevisiae is widely used to produce ethanol, industrial chemicals, lubricants, pharmaceuticals and more.

Understanding and...

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Universal Antibody Drug for HIV-1 Prevention and Immunotherapy

Design and characterization of 5 IAs.(A, B) Schematic diagrams show the...

Design and characterization of 5 IAs. (A, B) Schematic diagrams show the structures of IAs, which are scFv-hIgG-Fc–like molecules bearing antibody-binding domains to gp120 or human CD4. scFv, single-chain variable fragment; hIgG, human immunoglobulin G, VH, variable heavy chain; VL, variable light chain; CH, constant heavy chain. (C) The released IAs in culture supernatants were detected by Western blot analysis under reducing conditions. (D) Each IA displayed neutralizing activity against pseudovirus HIV-1ADA. (E) Paired IAs were tested for synergistic effects in a checkerboard neutralization assay. The synergy volumes of –50 to 50, 50 to 100, and >100 in a synergy plot at the 95% CI were used to define additive, slight synergistic, and synergistic effects, respectively...

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Can this Invasive Exotic Pest make better Materials for Industry and Medicine?

Although unappetizing in this lab shot, these creatures are already used for many other purposes, including as an ingredient in Asian cuisine. Credit: Johan Foster

Although unappetizing in this lab shot, these creatures are already used for many other purposes, including as an ingredient in Asian cuisine. Credit: Johan Foster

A NIST team has measured the best wood-to-pest ratio for the design of new composites. Tunicates are slimy invasive exotic pests that some people like to eat. Now they may be used to make UV-reflective, flexible construction materials. They have combined derivatives of two surplus materials – wood pulp and dried-up pieces of an invasive exotic pest – to form a new composite material that is flexible, sustainable, nontoxic and UV light-reflective. The material could soon be used in a wide variety of applications, including food packaging, biomedical devices, building construction and the design of cars, trucks and boats.

The key ...

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