Category Biology/Biotechnology

Gut Bacteria determine Speed of Tumor Growth in Pancreatic Cancer

Normal and cancerous pancreatic tissue. The blue background represents the cells that produce digestive juices supplied by the pancreas to the gut, and the red dots—seen only in the cancerous pancreas—represent the bacteria found to be a thousand times more abundant than normal.

Normal and cancerous pancreatic tissue. The blue background represents the cells that produce digestive juices supplied by the pancreas to the gut, and the red dots—seen only in the cancerous pancreas—represent the bacteria found to be a thousand times more abundant than normal.

Antibiotics may make immunotherapy more effective against pancreatic cancer. The population of bacteria in the pancreas increases more than a thousand fold in patients with pancreatic cancer, and becomes dominated by species that prevent the immune system from attacking tumor cells. These are the findings of a study conducted in mice and in patients with pancreatic ductal adenocarcinoma (PDA), a form of cancer that is usually fatal within two years...

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Hydrogel may help Heal Diabetic Ulcers

Rice University graduate student Nicole Carrejo analyzes a sample of K2(SL)6K2, an injectable hydrogel researchers believe may help accelerate the healing of diabetic ulcers. Credit: Jeff Fitlow/Rice University

Rice University graduate student Nicole Carrejo analyzes a sample of K2(SL)6K2, an injectable hydrogel researchers believe may help accelerate the healing of diabetic ulcers. Credit: Jeff Fitlow/Rice University

Invention could accelerate tissue growth compared with current treatment. A hydrogel invented at Rice University that is adept at helping the body heal may also be particularly good at treating wounds related to diabetes. The Rice lab of chemist and bioengineer Jeffrey Hartgerink reported this week that tests on diabetic animal models showed the injectable hydrogel significantly accelerated wound healing compared with another hydrogel often used in clinics. The study appears this week in the American Chemical Society journal ACS Biomaterials Science and Engineering...

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Scientists Mimic Neural Tissue in new research

Borrowing From the Eel: New breakthrough material could lead to future autonomous soft robotics, dual sensors and actuators for soft exoskeletons, or artificial skins. Credit: Image courtesy of U.S. Army Research Laboratory

Borrowing From the Eel: New breakthrough material could lead to future autonomous soft robotics, dual sensors and actuators for soft exoskeletons, or artificial skins. Credit: Image courtesy of U.S. Army Research Laboratory

U.S. Army-funded researchers at Brandeis University have discovered a process for engineering next-generation soft materials with embedded chemical networks that mimic the behavior of neural tissue. The breakthrough material may lead to autonomous soft robotics, dual sensors and actuators for soft exoskeletons, or artificial skins. The research lays the foundations for futuristic soft active matter with highly distributed and tightly integrated sensing, actuation, computation and control, said Dr...

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Stem Cells treat Macular Degeneration

Retinal pigmented epithelial cells

Stem cell-derived retinal pigmented epithelial cells. Cell borders are green and nuclei are red. Photo Credit: DENNIS CLEGG, UCSB CENTER FOR STEM CELL BIOLOGY AND ENGINEERING

Researchers helped develop a specially engineered retinal patch to treat people with sudden, severe sight loss. In July 2015, 86-year-old Douglas Waters developed severe age-related macular degeneration (AMD). He struggled to see things clearly, even when up close. A few months later, he became part of a clinical trial that used stem cell-derived ocular cells developed in part by researchers at UC Santa Barbara. His retinal eyepatch was implanted at Moorfields Eye Hospital, a National Health Service (NHS) facility in Waters’ hometown of London, England.

In the months before Waters’ surgery, his vision was poor and he ...

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