Category Biology/Biotechnology

Metabolic inflammation and NFкB-mediated neuroinflammatory responses in the NAc contribute to the expression of anxiodepressive behavior and heightened food cravings caused by a diet high in saturated fat and sugar.

A diet rich in saturated fat and sugar not only leads to obesity, it creates inflammation in the nucleus accumbens, a part of the brain that controls mood and the feeling of reward. And this inflammation can lead to depressive, anxious and compulsive behaviour and disrupt metabolism, according to a new study by researchers at the University of Montreal Hospital Research Centre (CRCHUM). Published in the journal Molecular Metabolism, the study on mice provides new evidence confirming the harmful effect of saturated fat on health.

“The depressive, anxious and compulsive behaviou...

A close up of DNA wires being drawn through the porous membrane. Credit: KTH

Scientists in Sweden today reported a nanoengineering innovation that offers hope for treatment of cancer, infections and other health problems – conductive wires of DNA enhanced with gold which could be used to electrically measure hundreds of biological processes simultaneously. While DNA nanowires have been in development for some time, the method developed at KTH Royal Institute of Technology and Stockholm University produces a unique 3D biosensor for better effectiveness than flat, 2D sensors. “Our geometry makes it much easier to measure several biomolecules simultaneously, and is also 100 times more sensitive,” says KTH Professor Wouter van der Wijngaart...

A section of “e-skin.” Credit: Jianliang Xiao / University of Colorado Boulder

University of Colorado Boulder researchers have developed a new type of malleable, self-healing and fully recyclable “electronic skin” that has applications ranging from robotics and prosthetic development to better biomedical devices. Electronic skin, known as e-skin, is a thin, translucent material that can mimic the function and mechanical properties of human skin. A number of different types and sizes of wearable e-skins are now being developed in labs around the world as researchers recognize their value in diverse medical, scientific and engineering fields.

The new CU Boulder e-skin has sensors embedded to measure pressure, temperature, humidity and air flow, said Assistant Professor Jianliang Xiao, who is...

Kidney glomeruli — constituent microscopic parts of the organ- were generated from human embryonic stem cells grown in plastic laboratory culture dishes. Credit: Image courtesy of University of Manchester

Scientists have successfully produced human kidney tissue within a living organism which is able to produce urine, a first for medical science. It signifies a significant milestone in the development of treatment for kidney disease. Kidney glomeruli – constituent microscopic parts of the organ- were generated from human embryonic stem cells grown in plastic laboratory culture dishes containing a nutrient broth known as culture medium, containing molecules to promote kidney development...