Category Biology/Biotechnology

Electricity-generating bacteria may power future innovations

ajo franklin and Biki Bapi Kundu

Researchers uncover a surprising survival strategy that could reshape biotech and energy systems. A team led by Rice University bioscientist Caroline Ajo-Franklin has discovered how certain bacteria breathe by generating electricity, using a natural process that pushes electrons into their surroundings instead of breathing on oxygen. The findings, published in Cell last month, could enable new developments in clean energy and industrial biotechnology.

By identifying how these bacteria expel electrons externally, the researchers offer a glimpse into a previously hidden strategy of bacterial life. This work, which merges biology with electrochemistry, lays the groundwork for future technologies that harness the unique capabilities of these microscopic organisms.

“Our research not ...

Read More

Compromised synapse-clearing ability linked to autism

Japanese researchers link compromised synapse-clearing ability to autism
Monocyte-derived macrophages modelled microglial function to explore impaired synaptic clearance in autism spectrum disorder (white: neurites of hiPS cell-derived neurons, green: macrophages from individuals with ASD, red: PSD95, a scaffolding protein in the postsynaptic region, blue: nuclei). Credit: Michihiro Toritsuka from Fujita Health University School of Medicine, Japan

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of behavior or interests.

A growing body of research suggests that neurobiological changes, particularly abnormalities in dendritic spines, tiny protrusions on nerve cells where synapses form, may be a hallmark of ASD...

Read More

Are ‘zombie’ skin cells harmful or helpful? The answer may be in their shapes

Skin-related fibroblasts with nuclei stained green and f-actin stained red.

Researchers identified three types of zombie skin cells; only one gets worse with age. Researchers have identified three subtypes of senescent skin cells with distinct shapes, biomarkers, and functions – an advance that could equip scientists with the ability to target and kill the harmful types while leaving the helpful ones intact.

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.

New findings may explain why: Not all senescent skin cells are the same. They were published today in the journal Science Advances.

“We’ve known that senescent skin cells are...

Read More

How bacteria in our aging guts can elevate risk of leukemia and perhaps more

New findings in Nature reveal how age-related gut changes fuel the growth of pre-leukemic blood cells. Scientists at Cincinnati Children’s along with an international team of researchers have discovered a surprising new connection between gut health and blood cancer risk — one that could transform how we think about aging, inflammation, and the early stages of leukemia.

As we grow older — or in some cases, when gut health is compromised by disease — changes in the intestinal lining allow certain bacteria to leak their byproducts into the bloodstream. One such molecule, produced by specific bacteria, acts as a signal that accelerates the expansion of dormant, pre-leukemic blood cells, a critical step to developing full-blown leukemia.

The team’s findings — published April 23, 202...

Read More