Category Biology/Biotechnology

Triple-Threat Cancer-fighting Polymer Capsules for guided Drug delivery

This guided drug delivery system targets solid tumors. Credit: UAB

This guided drug delivery system targets solid tumors. Credit: UAB

These microcarriers may offer an entirely different approach to treating solid human tumors of numerous pathologic subtypes by delivering their encapsulated drug cargo to a tumor and protecting against collateral tissue damage. These multilayer capsules show three traits that have been difficult to achieve in a single entity. They have good imaging contrast that allows detection with low-power ultrasound, they can stably and efficiently encapsulate the cancer drug doxorubicin, and both a low- and higher-power dose of ultrasound can trigger the release of that cargo.

These 3 features create a guided drug delivery system to target solid tumors...

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Not a Pipe Dream anymore. Space-Farming: A long legacy leading us to Mars

Research into space farming has resulted in numerous Earth-based advances (e.g., LED lighting for greenhouse and vertical farm applications; new seed potato propagation techniques, etc.) There are still many technical challenges, but plants and associated biological systems can and will be a major component of the systems that keep humans alive when we establish ourselves on the Moon, Mars and beyond. Credit: NASA

Research into space farming has resulted in numerous Earth-based advances (e.g., LED lighting for greenhouse and vertical farm applications; new seed potato propagation techniques, etc.) There are still many technical challenges, but plants and associated biological systems can and will be a major component of the systems that keep humans alive when we establish ourselves on the Moon, Mars and beyond. Credit: NASA

How plants are grown beyond Earth? Plants, and specifically crop plants, will be a major component of proposed regenerative life-support systems as they provide food, oxygen, scrub carbon dioxide, and aid in water recycling – all in a self-regenerating or ‘bioregenerative’ fashion...

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Beating Deadly Pneumonia with Hormones

Borna Mehrad, MBBS (left), and Kathryn Michels, both of the University of Virginia School of Medicine, have identified a hormone that helps the body fight off the spread of bacterial pneumonia. The discovery may offer a simple way to help vulnerable patients.

Borna Mehrad, MBBS (left), and Kathryn Michels, both of the University of Virginia School of Medicine, have identified a hormone that helps the body fight off the spread of bacterial pneumonia. The discovery may offer a simple way to help vulnerable patients.

A hormone responsible for controlling iron metabolism helps fight off a severe form of bacterial pneumonia, and that discovery may offer a simple way to help vulnerable patients. Hepcidin, is produced in the liver and limits the spread of the bacteria by hiding the iron in the blood that the bacteria need to survive and grow. Stimulating hepcidin production in patients who do not produce it well, such as people with iron overload or liver disease, may help their bodies effectively starve the bacteria to death...

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Modern Alchemy creates Luminescent Iron Molecules

iron complex [Fe(btz)3]3+

iron complex [Fe(btz)3]3+

A group of researchers have made the first iron-based molecule capable of emitting light. This could contribute to the development of affordable and environmentally friendly materials for e.g. solar cells, light sources and displays. For over 50 years, chemists have developed metal-based dye molecules for a wide range of different applications, such as displays and solar cells. This would ideally involve common and environmentally friendly metals like iron, but despite a number of attempts no one has been able to develop an iron-based dye molecule that can emit light until now. Researchers around the world have therefore instead largely had to resort to various rare and precious metals, such as ruthenium, which have more easily provided the desired properties.

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