Category Biology/Biotechnology

Ceftriaxone partially restores glutamate dynamic deficits around Aβ deposits.

New research from the Djavad Mowafaghian Centre for Brain Health at UBC has found a way to partially restore brain cell communication around areas damaged by plaques associated with Alzheimer’s disease. The findings, published this week in Nature Communications, demonstrate a possible target and a potential drug treatment to reduce damage to the brain that occurs in the early stages of Alzheimer’s disease. Using Ceftriaxone, an FDA-approved antibiotic used to treat bacterial infections, researchers were able to reduce synaptic disruption and clear the lines of neuronal communication in mice.

Amyloid plaques of -amyloid deposits develop in brain regions of patients with Alzheimer’s disease, These plaques are link...

Increased Activation in Control Regions in Older Adults Tested at a Peak Time of Day.

As you age, you may find it more difficult to focus on certain tasks. But while distractions can be frustrating, they may not be as bad as we think. Researchers at the University of Toronto and Harvard University suggest that there may be some benefits to reduced focus, especially >50yo. Using behavioral studies and neuroimaging, they discuss how being easily distracted can help adults with, eg. problem solving and learning new information.

“Different types of tasks benefit from a more broad focus of attention, and this is usually seen in tasks that involve thinking creatively or using information that was previously irrelevant,” says Tarek Amer, Ph.D.

When people have high cognitive control, they are abl...

Researchers used acoustic waves with a frequency of 20 megaHertz to manipulate fluids, droplets and particles in nanoslits that are 50 to 250 nanometers tall. To fill the channels, researchers applied the acoustic waves in the same direction as the fluid moving into the channels. To drain the channels, the sound waves were applied in the opposite direction. Credit: James Friend/UC San Diego

A team of mechanical engineers at the University of California San Diego has successfully used acoustic waves to move fluids through small channels at the nanoscale. The breakthrough is a first step toward the manufacturing of small, portable devices that could be used for drug discovery and microrobotics applications...

The Bochum-based team: Piyanut Pinyou, Wolfgang Schuhmann, Sabine Alsaoub and Felipe Conzuelo (from left). Credit: © RUB, Marquard

Researchers have developed a hybrid of a fuel cell and capacitor on a biocatalytic basis. With the aid of enzymatic processes, what’s known as a biosupercapacitor efficiently generates and stores energy. The trick: the enzymes are embedded in a stable polymer gel, which can store a large amount of energy. Generating energy and saving it with as little loss as possible is one of the major challenges for today’s society. Energy production and storage usually take place in different systems – which is inefficient. This is different in the new biosupercapacitor, which combines both processes.

“Such a technology could, for instance, be interesting for miniaturised ...