Category Biology/Biotechnology

Model Maps out Molecular Roots of Learning and Memory Formation

Illustration of the neuron, dendrites, and dendritic spines.

Illustration of the neuron, dendrites, and dendritic spines.

A team has built a mathematical model that describes the molecular events associated with the beginning stage of learning and memory formation in the human brain. The research paves the way for understanding cognitive function and neurodegenerative diseases – at the molecular and cellular levels. The study focuses on the dynamics of dendritic spines, thorny structures that allow neurons to communicate with each other. When a spine receives a signal from another neuron, it responds by rapidly expanding in volume ie transient spine expansion.

Transient spine expansion is one of the early events leading up to learning and memory formation...

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New Sensor could help fight deadly Bacterial infections

Schematic diagram of the sensor structure

Schematic diagram of the sensor structure

The sensor can detect E. coli bacteria in 15-20 minutes, much faster than traditional lab tests, over a wide temperature range . E.coli can be transmitted in contaminated food and water, posing particular risks to children and the elderly. In the late spring of 2011 a serious outbreak of E.coli bacteria sickened thousands of people in Germany and killed more than 50. “Using currently available technologies, which are mostly based on amplification of the sample, it takes several hours to days to detect the presence of bacteria. A fast and accurate detection alternative is, therefore, preferable over the existing technology,” said Saurabh Mani Tripathi, a physicist at the Indian Institute of Technology Kanpur.

The new sensor uses bacteriophages – viru...

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The fruit of ‘Asam Keping’ tree can be used to Prevent Atherosclerosis according to research

Asam keping fruit

Asam keping

Dr Suraya A. Sani, recent PhD graduate from The University of Nottingham Malaysia Campus (UNMC), has been working with a tropical fruit, locally called asam keping, under the supervision of Dr Teng-Jin Khoo at UNMC’s School of Pharmacy. Funded by the Sarawak Tunku Abdul Rahman Scholarship, she was able to spend her time on research work for the first two years at UNMC and a year working on her research at the Centre for BioMolecular Sciences at University Park, The University of Nottingham, UK under the co-supervision of Professor Dr Jonas Emsley.

Dr Suraya A. Sani conducts research on the medicinal properties of the Garcinia plant species; a plant species which is largely available in Malaysia and throughout Southeast Asia...

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Common Bacteria show promise for treating Celiac disease

 (A) Image of Rothia mucilaginosa grown on a blood agar plate showing mucoid, grayish colonies after incubation at 37℃ for 48 hr. (B) Microscopic image of the cultured isolates showing clusters of gram-positive cocci (Gram stain, ×1,000).

(A) Image of Rothia mucilaginosa grown on a blood agar plate showing mucoid, grayish colonies after incubation at 37℃ for 48 hr. (B) Microscopic image of the cultured isolates showing clusters of gram-positive cocci (Gram stain, ×1,000).

Researchers have isolated an enzyme from bacteria present in human saliva that has potential as a therapy for celiac disease (CD). An estimated 3 million people in the U.S. have celiac disease. Currently, the main course of treatment for people with CD is adherence to a strict gluten-free diet. “Gluten are proline- and glutamine-rich proteins present in wheat, barley and rye, and contain the immunogenic sequences that drive celiac disease (CD),” the researchers wrote...

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