Category Biology/Biotechnology

Next-Gen Holographic Microscope for 3D live Cell Imaging

3D Images of Representative Biological Cells Taken with the HT-1. Credit: Copyright KAIST

3D Images of Representative Biological Cells Taken with the HT-1. Credit: Copyright KAIST

Researchers at Korea Advanced Institute of Science and Technology (KAIST) have developed a revolutionary bio-medical imaging tool, the holotomography HT-1, to view and analyze cells, which is commercially available. Professor Park collaborated with TomoCube’s R&D team to develop a state-of-the-art, 2D/3D/4D holographic microscope that would allow a real-time label-free visualization of biological cells and tissues.

The HT is an optical analogy of X-ray computed tomography (CT). Both X-ray CT and HT share the same physical principle — the inverse of wave scattering. The difference is that HT uses laser illumination whereas X-ray CT uses X-ray beams...

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How the Brain Processes Emotions

Two neurons of the basolateral amygdala. MIT neuroscientists have found that these neurons play a key role in separating information about positive and negative experiences. Credit: Anna Beyeler and Praneeth Namburi

Two neurons of the basolateral amygdala. MIT neuroscientists have found that these neurons play a key role in separating information about positive and negative experiences. Credit: Anna Beyeler and Praneeth Namburi

A new study reveals how 2 populations of neurons contribute to the brain’s inability to correctly assign emotional associations to events, eg those who are depressed often do not feel happy even when experiencing something that they normally enjoy. Learning how this information is routed and misrouted could shed light on mental illnesses including depression, addiction, anxiety, and posttraumatic stress disorder.

In a previous study, Tye’s lab identified 2 populations of neurons involved in processing positive and negative emotions...

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Zika virus Structure revealed, a critical advance in the development of Treatments & Vaccines

A representation of the surface of the Zika virus is shown. A team led by Purdue University researchers is the first to determine the structure of the Zika virus, which reveals insights critical to the development of effective antiviral treatments and vaccines. Credit: Purdue University image/courtesy of Kuhn and Rossmann research groups

A representation of the surface of the Zika virus is shown. A team led by Purdue University researchers is the first to determine the structure of the Zika virus, which reveals insights critical to the development of effective antiviral treatments and vaccines. Credit: Purdue University image/courtesy of Kuhn and Rossmann research groups

The Purdue Uni team also identified regions within the Zika virus structure where it differs from other flaviviruses, the family of viruses to which Zika belongs that includes dengue, West Nile, yellow fever, Japanese encephalitis and tick-borne encephalitic viruses...

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Handheld Surgical ‘Pen’ Prints Human Stem Cells

A new 3D printing pen to 'draw' human stem cells in freeform patterns. Using a hydrogel bio-ink to carry and support living human stem cells, and a low powered light source to solidify the ink, the pen delivers a cell survival rate in excess of 97%. Credit: Image courtesy of ARC Centre of Excellence for Electromaterials Science

A new 3D printing pen to ‘draw’ human stem cells in freeform patterns. Using a hydrogel bio-ink to carry and support living human stem cells, and a low powered light source to solidify the ink, the pen delivers a cell survival rate in excess of 97%. Credit: Image courtesy of ARC Centre of Excellence for Electromaterials Science

In a landmark proof-of-concept experiment, Australian researchers have used a handheld 3D printing pen to ‘draw’ human stem cells in freeform patterns with extremely high survival rates. The device, developed out of collaboration between ARC Centre of Excellence for Electromaterials Science (ACES) researchers and orthopaedic surgeons at St Vincent’s Hospital, Melbourne, is designed to allow surgeons to sculpt customised cartilage implants during surgery.

Using a hyd...

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